G221-0970 Screening compound: 1-{[5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl](phenyl)methyl}-4-phenyl-1,2,3,6-tetrahydropyridine

G221-0970 Screening compound: 1-{[5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl](phenyl)methyl}-4-phenyl-1,2,3,6-tetrahydropyridine
G221-0970 Screening compound: 1-{[5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl](phenyl)methyl}-4-phenyl-1,2,3,6-tetrahydropyridine alternative view

Chemical Structure Depiction of ChemDiv screening compound G221-0970
1-{[5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl](phenyl)methyl}-4-phenyl-1,2,3,6-tetrahydropyridine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G221-0970

Molecular Formula

C26H22ClN3O (C26 H22 ClN3 O)

Compound Name

1-{[5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl](phenyl)methyl}-4-phenyl-1,2,3,6-tetrahydropyridine

IUPAC name

1-{[5-(4-chlorophenyl)-134-oxadiazol-2-yl](phenyl)methyl}-4-phenyl-1236-tetrahydropyridine

SMILES

Clc(cc1)ccc1-c1nnc(C(c2ccccc2)N(CC2)CC=C2c2ccccc2)o1

InChI

InChI=1S/C26H22ClN3O/c27-23-13-11-22(12-14-23)25-28-29-26(31-25)24(21-9-5-2-6-10-21)30-17-15-20(16-18-30)19-7-3-1-4-8-19/h1-15,24H,16-18H2/t24-/m1/s1

InChI Key

FYQYBNZAOBSWBP-XMMPIXPASA-N

MDL Number (MFCD)

MFCD14988695

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

427.93

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

6.540

Distribution Coefficient, logD

6.540

Water Solubility, LogSw

-6.74

Polar Surface Area

33.236

Acid Dissociation Constant (pKa)

26.97

Base Dissociation Constant (pKb)

1.00

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

15.40

G221-0970 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

DGK Inhibitors Library (10558 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Hemic and lymphatic
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with G221-0970 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G221-0970?
Check Price and Availability of G221-0970, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G221-0970 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G221-0970
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G221-0970
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G221-0970 available by request