G227-0042 Screening compound: 2-[4-(2H-1,3-benzodioxol-5-yl)-1,3-thiazol-2-yl]-4-(4-chlorophenyl)-1,3-thiazole

G227-0042 Screening compound: 2-[4-(2H-1,3-benzodioxol-5-yl)-1,3-thiazol-2-yl]-4-(4-chlorophenyl)-1,3-thiazole
G227-0042 Screening compound: 2-[4-(2H-1,3-benzodioxol-5-yl)-1,3-thiazol-2-yl]-4-(4-chlorophenyl)-1,3-thiazole alternative view

Chemical Structure Depiction of ChemDiv screening compound G227-0042
2-[4-(2H-1,3-benzodioxol-5-yl)-1,3-thiazol-2-yl]-4-(4-chlorophenyl)-1,3-thiazole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G227-0042

Molecular Formula

C19H11ClN2O2S2 (C19 H11 ClN2 O2 S2)

Compound Name

2-[4-(2H-1,3-benzodioxol-5-yl)-1,3-thiazol-2-yl]-4-(4-chlorophenyl)-1,3-thiazole

IUPAC name

2-[4-(2H-13-benzodioxol-5-yl)-13-thiazol-2-yl]-4-(4-chlorophenyl)-13-thiazole

SMILES

Clc(cc1)ccc1-c1csc(-c2nc(-c(cc3)cc4c3OCO4)cs2)n1

InChI

InChI=1S/C19H11ClN2O2S2/c20-13-4-1-11(2-5-13)14-8-25-18(21-14)19-22-15(9-26-19)12-3-6-16-17(7-12)24-10-23-16/h1-9H,10H2

InChI Key

VOGKWIVZMABYTE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14988827

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

398.89

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

6.896

Distribution Coefficient, logD

6.896

Water Solubility, LogSw

-6.84

Polar Surface Area

36.550

Acid Dissociation Constant (pKa)

37.89

Base Dissociation Constant (pKb)

-0.65

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

5.30

G227-0042 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with G227-0042 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G227-0042?
Check Price and Availability of G227-0042, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G227-0042 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G227-0042
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G227-0042
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G227-0042 available by request