G227-0531 Screening compound: 2-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-5-methyl-4-(4-methylphenyl)-1,3-thiazole

G227-0531 Screening compound: 2-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-5-methyl-4-(4-methylphenyl)-1,3-thiazole
G227-0531 Screening compound: 2-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-5-methyl-4-(4-methylphenyl)-1,3-thiazole alternative view

Chemical Structure Depiction of ChemDiv screening compound G227-0531
2-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-5-methyl-4-(4-methylphenyl)-1,3-thiazole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G227-0531

Molecular Formula

C20H15ClN2S2 (C20 H15 ClN2 S2)

Compound Name

2-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-5-methyl-4-(4-methylphenyl)-1,3-thiazole

IUPAC name

2-[4-(4-chlorophenyl)-13-thiazol-2-yl]-5-methyl-4-(4-methylphenyl)-13-thiazole

SMILES

Cc1c(-c2ccc(C)cc2)nc(-c2nc(-c(cc3)ccc3Cl)cs2)s1

InChI

InChI=1S/C20H15ClN2S2/c1-12-3-5-15(6-4-12)18-13(2)25-20(23-18)19-22-17(11-24-19)14-7-9-16(21)10-8-14/h3-11H,1-2H3

InChI Key

YTXSOGWBRJNJBM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14988887

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

382.94

Hydrogen Bond Acceptors Count

2.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

2

Partition Coefficient, logP

7.508

Distribution Coefficient, logD

7.508

Water Solubility, LogSw

-6.87

Polar Surface Area

20.205

Acid Dissociation Constant (pKa)

26.68

Base Dissociation Constant (pKb)

-0.53

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

10.00

G227-0531 in Drug Discovery

Included in Screening Libraries

Epitranscriptome Focused Small Molecule Library (20952 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with G227-0531 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G227-0531?
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What is the minimum amount of G227-0531 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G227-0531
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G227-0531
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G227-0531 available by request