G227-0542 Screening compound: 2-[4-(4-bromophenyl)-1,3-thiazol-2-yl]-5-methyl-4-(4-methylphenyl)-1,3-thiazole

G227-0542 Screening compound: 2-[4-(4-bromophenyl)-1,3-thiazol-2-yl]-5-methyl-4-(4-methylphenyl)-1,3-thiazole
G227-0542 Screening compound: 2-[4-(4-bromophenyl)-1,3-thiazol-2-yl]-5-methyl-4-(4-methylphenyl)-1,3-thiazole alternative view

Chemical Structure Depiction of ChemDiv screening compound G227-0542
2-[4-(4-bromophenyl)-1,3-thiazol-2-yl]-5-methyl-4-(4-methylphenyl)-1,3-thiazole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G227-0542

Molecular Formula

C20H15BrN2S2 (C20 H15 BrN2 S2)

Compound Name

2-[4-(4-bromophenyl)-1,3-thiazol-2-yl]-5-methyl-4-(4-methylphenyl)-1,3-thiazole

IUPAC name

2-[4-(4-bromophenyl)-13-thiazol-2-yl]-5-methyl-4-(4-methylphenyl)-13-thiazole

SMILES

Cc1c(-c2ccc(C)cc2)nc(-c2nc(-c(cc3)ccc3Br)cs2)s1

InChI

InChI=1S/C20H15BrN2S2/c1-12-3-5-15(6-4-12)18-13(2)25-20(23-18)19-22-17(11-24-19)14-7-9-16(21)10-8-14/h3-11H,1-2H3

InChI Key

BUTGGMSCFLZQPV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14988896

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

427.39

Hydrogen Bond Acceptors Count

2.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

2

Partition Coefficient, logP

7.747

Distribution Coefficient, logD

7.747

Water Solubility, LogSw

-6.00

Polar Surface Area

20.205

Acid Dissociation Constant (pKa)

26.68

Base Dissociation Constant (pKb)

-0.53

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

10.00

G227-0542 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Epitranscriptome Focused Small Molecule Library (20952 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with G227-0542 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G227-0542?
Check Price and Availability of G227-0542, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G227-0542 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G227-0542
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G227-0542
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G227-0542 available by request