G227-0977 Screening compound: 4-(4-chlorophenyl)-5-methyl-2-[4-(thiophen-2-yl)-1,3-thiazol-2-yl]-1,3-thiazole

G227-0977 Screening compound: 4-(4-chlorophenyl)-5-methyl-2-[4-(thiophen-2-yl)-1,3-thiazol-2-yl]-1,3-thiazole
G227-0977 Screening compound: 4-(4-chlorophenyl)-5-methyl-2-[4-(thiophen-2-yl)-1,3-thiazol-2-yl]-1,3-thiazole alternative view

Chemical Structure Depiction of ChemDiv screening compound G227-0977
4-(4-chlorophenyl)-5-methyl-2-[4-(thiophen-2-yl)-1,3-thiazol-2-yl]-1,3-thiazole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G227-0977

Molecular Formula

C17H11ClN2S3 (C17 H11 ClN2 S3)

Compound Name

4-(4-chlorophenyl)-5-methyl-2-[4-(thiophen-2-yl)-1,3-thiazol-2-yl]-1,3-thiazole

IUPAC name

4-(4-chlorophenyl)-5-methyl-2-[4-(thiophen-2-yl)-13-thiazol-2-yl]-13-thiazole

SMILES

Cc1c(-c(cc2)ccc2Cl)nc(-c2nc(-c3cccs3)cs2)s1

InChI

InChI=1S/C17H11ClN2S3/c1-10-15(11-4-6-12(18)7-5-11)20-17(23-10)16-19-13(9-22-16)14-3-2-8-21-14/h2-9H,1H3

InChI Key

LPOVUPCROBPWEE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14988921

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

374.94

Hydrogen Bond Acceptors Count

2.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

2

Partition Coefficient, logP

6.691

Distribution Coefficient, logD

6.691

Water Solubility, LogSw

-6.77

Polar Surface Area

21.224

Acid Dissociation Constant (pKa)

26.68

Base Dissociation Constant (pKb)

-0.38

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

5.90

G227-0977 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Epitranscriptome Focused Small Molecule Library (20952 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with G227-0977 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G227-0977?
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What is the minimum amount of G227-0977 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G227-0977
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G227-0977
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G227-0977 available by request