G227-1641 Screening compound: 4-(2H-1,3-benzodioxol-5-yl)-2-[4-(3,4-dimethylphenyl)-1,3-thiazol-2-yl]-1,3-thiazole

G227-1641 Screening compound: 4-(2H-1,3-benzodioxol-5-yl)-2-[4-(3,4-dimethylphenyl)-1,3-thiazol-2-yl]-1,3-thiazole
G227-1641 Screening compound: 4-(2H-1,3-benzodioxol-5-yl)-2-[4-(3,4-dimethylphenyl)-1,3-thiazol-2-yl]-1,3-thiazole alternative view

Chemical Structure Depiction of ChemDiv screening compound G227-1641
4-(2H-1,3-benzodioxol-5-yl)-2-[4-(3,4-dimethylphenyl)-1,3-thiazol-2-yl]-1,3-thiazole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G227-1641

Molecular Formula

C21H16N2O2S2 (C21 H16 N2 O2 S2)

Compound Name

4-(2H-1,3-benzodioxol-5-yl)-2-[4-(3,4-dimethylphenyl)-1,3-thiazol-2-yl]-1,3-thiazole

IUPAC name

4-(2H-13-benzodioxol-5-yl)-2-[4-(34-dimethylphenyl)-13-thiazol-2-yl]-13-thiazole

SMILES

Cc(cc1)c(C)cc1-c1csc(-c2nc(-c(cc3)cc4c3OCO4)cs2)n1

InChI

InChI=1S/C21H16N2O2S2/c1-12-3-4-14(7-13(12)2)16-9-26-20(22-16)21-23-17(10-27-21)15-5-6-18-19(8-15)25-11-24-18/h3-10H,11H2,1-2H3

InChI Key

GPDBRUDZGCLNHF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14988940

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

392.5

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

7.164

Distribution Coefficient, logD

7.164

Water Solubility, LogSw

-5.79

Polar Surface Area

36.550

Acid Dissociation Constant (pKa)

28.01

Base Dissociation Constant (pKb)

-0.65

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

14.30

G227-1641 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

Targeted Diversity Library (40567 compounds)

Epitranscriptome Focused Small Molecule Library (20952 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with G227-1641 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G227-1641?
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What is the minimum amount of G227-1641 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G227-1641
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G227-1641
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G227-1641 available by request