G240-0819 Screening compound: 2-(morpholine-4-carbonyl)-N-[3-(trifluoromethyl)phenyl]-2,3-dihydro-1,4-benzodioxine-6-sulfonamide

G240-0819 Screening compound: 2-(morpholine-4-carbonyl)-N-[3-(trifluoromethyl)phenyl]-2,3-dihydro-1,4-benzodioxine-6-sulfonamide
G240-0819 Screening compound: 2-(morpholine-4-carbonyl)-N-[3-(trifluoromethyl)phenyl]-2,3-dihydro-1,4-benzodioxine-6-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G240-0819
2-(morpholine-4-carbonyl)-N-[3-(trifluoromethyl)phenyl]-2,3-dihydro-1,4-benzodioxine-6-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G240-0819

Molecular Formula

C20H19F3N2O6S (C20 H19 F3 N2 O6 S)

Compound Name

2-(morpholine-4-carbonyl)-N-[3-(trifluoromethyl)phenyl]-2,3-dihydro-1,4-benzodioxine-6-sulfonamide

IUPAC name

2-(morpholine-4-carbonyl)-N-[3-(trifluoromethyl)phenyl]-23-dihydro-14-benzodioxine-6-sulfonamide

SMILES

O=C(C1Oc(ccc(S(Nc2cc(C(F)(F)F)ccc2)(=O)=O)c2)c2OC1)N1CCOCC1

InChI

InChI=1S/C20H19F3N2O6S/c21-20(22,23)13-2-1-3-14(10-13)24-32(27,28)15-4-5-16-17(11-15)30-12-18(31-16)19(26)25-6-8-29-9-7-25/h1-5,10-11,18,24H,6-9,12H2/t18-/m1/s1

InChI Key

NPPAFBIQRNGCHK-GOSISDBHSA-N

MDL Number (MFCD)

MFCD14989453

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

472.44

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.555

Distribution Coefficient, logD

2.438

Water Solubility, LogSw

-3.21

Polar Surface Area

80.882

Acid Dissociation Constant (pKa)

7.91

Base Dissociation Constant (pKb)

-2.05

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

35.00

G240-0819 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

PI3K-Targeted Library (17255 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with G240-0819 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G240-0819?
Check Price and Availability of G240-0819, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G240-0819 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G240-0819
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G240-0819
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G240-0819 available by request