G266-0624 Screening compound: 1-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-[1,3-dimethyl-2-oxo-6-(pyrrolidin-1-yl)-2,3-dihydro-1H-1,3-benzodiazol-5-yl]urea

G266-0624 Screening compound: 1-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-[1,3-dimethyl-2-oxo-6-(pyrrolidin-1-yl)-2,3-dihydro-1H-1,3-benzodiazol-5-yl]urea
G266-0624 Screening compound: 1-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-[1,3-dimethyl-2-oxo-6-(pyrrolidin-1-yl)-2,3-dihydro-1H-1,3-benzodiazol-5-yl]urea alternative view

Chemical Structure Depiction of ChemDiv screening compound G266-0624
1-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-[1,3-dimethyl-2-oxo-6-(pyrrolidin-1-yl)-2,3-dihydro-1H-1,3-benzodiazol-5-yl]urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G266-0624

Molecular Formula

C22H25N5O4 (C22 H25 N5 O4)

Compound Name

1-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-[1,3-dimethyl-2-oxo-6-(pyrrolidin-1-yl)-2,3-dihydro-1H-1,3-benzodiazol-5-yl]urea

IUPAC name

1-(23-dihydro-14-benzodioxin-6-yl)-3-[13-dimethyl-2-oxo-6-(pyrrolidin-1-yl)-23-dihydro-1H-13-benzodiazol-5-yl]urea

SMILES

CN(c(cc(c(N1CCCC1)c1)NC(Nc(cc2)cc3c2OCCO3)=O)c1N1C)C1=O

InChI

InChI=1S/C22H25N5O4/c1-25-17-12-15(16(27-7-3-4-8-27)13-18(17)26(2)22(25)29)24-21(28)23-14-5-6-19-20(11-14)31-10-9-30-19/h5-6,11-13H,3-4,7-10H2,1-2H3,(H2,23,24,28)

InChI Key

CDVAHMSLEUQDMM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27211763

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

423.47

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.948

Distribution Coefficient, logD

2.947

Water Solubility, LogSw

-3.45

Polar Surface Area

68.869

Acid Dissociation Constant (pKa)

10.00

Base Dissociation Constant (pKb)

10.69

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

36.40

G266-0624 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Anticancer Library (62698 compounds)

GPCR Targeted Library (31838 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • GPCR
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G266-0624 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G266-0624?
Check Price and Availability of G266-0624, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G266-0624 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G266-0624
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G266-0624
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G266-0624 available by request