G266-0635 Screening compound: 3-(butan-2-yl)-1-[1,3-dimethyl-2-oxo-6-(pyrrolidin-1-yl)-2,3-dihydro-1H-1,3-benzodiazol-5-yl]urea

G266-0635 Screening compound: 3-(butan-2-yl)-1-[1,3-dimethyl-2-oxo-6-(pyrrolidin-1-yl)-2,3-dihydro-1H-1,3-benzodiazol-5-yl]urea
G266-0635 Screening compound: 3-(butan-2-yl)-1-[1,3-dimethyl-2-oxo-6-(pyrrolidin-1-yl)-2,3-dihydro-1H-1,3-benzodiazol-5-yl]urea alternative view

Chemical Structure Depiction of ChemDiv screening compound G266-0635
3-(butan-2-yl)-1-[1,3-dimethyl-2-oxo-6-(pyrrolidin-1-yl)-2,3-dihydro-1H-1,3-benzodiazol-5-yl]urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G266-0635

Molecular Formula

C18H27N5O2 (C18 H27 N5 O2)

Compound Name

3-(butan-2-yl)-1-[1,3-dimethyl-2-oxo-6-(pyrrolidin-1-yl)-2,3-dihydro-1H-1,3-benzodiazol-5-yl]urea

IUPAC name

3-(butan-2-yl)-1-[13-dimethyl-2-oxo-6-(pyrrolidin-1-yl)-23-dihydro-1H-13-benzodiazol-5-yl]urea

SMILES

CCC(C)NC(Nc(c(N1CCCC1)c1)cc(N2C)c1N(C)C2=O)=O

InChI

InChI=1S/C18H27N5O2/c1-5-12(2)19-17(24)20-13-10-15-16(22(4)18(25)21(15)3)11-14(13)23-8-6-7-9-23/h10-12H,5-9H2,1-4H3,(H2,19,20,24)/t12-/m0/s1

InChI Key

IGXZFDSEFZOQGQ-LBPRGKRZSA-N

MDL Number (MFCD)

MFCD27211773

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

345.44

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.791

Distribution Coefficient, logD

2.789

Water Solubility, LogSw

-3.35

Polar Surface Area

54.081

Acid Dissociation Constant (pKa)

10.33

Base Dissociation Constant (pKb)

2.20

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

55.60

G266-0635 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Cardiovascular Library (22201 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Cardiovascular
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with G266-0635 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G266-0635?
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What is the minimum amount of G266-0635 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G266-0635
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G266-0635
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G266-0635 available by request