G266-1176 Screening compound: 3-[1,3-diethyl-2-oxo-6-(piperidin-1-yl)-2,3-dihydro-1H-1,3-benzodiazol-5-yl]-1-(2,4-difluorophenyl)urea

G266-1176 Screening compound: 3-[1,3-diethyl-2-oxo-6-(piperidin-1-yl)-2,3-dihydro-1H-1,3-benzodiazol-5-yl]-1-(2,4-difluorophenyl)urea
G266-1176 Screening compound: 3-[1,3-diethyl-2-oxo-6-(piperidin-1-yl)-2,3-dihydro-1H-1,3-benzodiazol-5-yl]-1-(2,4-difluorophenyl)urea alternative view

Chemical Structure Depiction of ChemDiv screening compound G266-1176
3-[1,3-diethyl-2-oxo-6-(piperidin-1-yl)-2,3-dihydro-1H-1,3-benzodiazol-5-yl]-1-(2,4-difluorophenyl)urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G266-1176

Molecular Formula

C23H27F2N5O2 (C23 H27 F2 N5 O2)

Compound Name

3-[1,3-diethyl-2-oxo-6-(piperidin-1-yl)-2,3-dihydro-1H-1,3-benzodiazol-5-yl]-1-(2,4-difluorophenyl)urea

IUPAC name

3-[13-diethyl-2-oxo-6-(piperidin-1-yl)-23-dihydro-1H-13-benzodiazol-5-yl]-1-(24-difluorophenyl)urea

SMILES

CCN(c(c(N1CC)c2)cc(NC(Nc(ccc(F)c3)c3F)=O)c2N2CCCCC2)C1=O

InChI

InChI=1S/C23H27F2N5O2/c1-3-29-20-13-18(27-22(31)26-17-9-8-15(24)12-16(17)25)19(28-10-6-5-7-11-28)14-21(20)30(4-2)23(29)32/h8-9,12-14H,3-7,10-11H2,1-2H3,(H2,26,27,31)

InChI Key

HXPKBJOGUOPZPP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27211977

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

443.5

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.275

Distribution Coefficient, logD

5.233

Water Solubility, LogSw

-5.17

Polar Surface Area

51.900

Acid Dissociation Constant (pKa)

8.80

Base Dissociation Constant (pKb)

10.17

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

39.10

G266-1176 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer

References: we are preparing a list of scientific research reports with G266-1176 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G266-1176?
Check Price and Availability of G266-1176, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G266-1176 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G266-1176
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G266-1176
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G266-1176 available by request