G266-1387 Screening compound: 3-[1,3-DIETHYL-2-OXO-6-(PYRROLIDIN-1-YL)-2,3-DIHYDRO-1H-1,3-BENZODIAZOL-5-YL]-1-(2,5-DIFLUOROPHENYL)UREA

G266-1387 Screening compound: 3-[1,3-DIETHYL-2-OXO-6-(PYRROLIDIN-1-YL)-2,3-DIHYDRO-1H-1,3-BENZODIAZOL-5-YL]-1-(2,5-DIFLUOROPHENYL)UREA
G266-1387 Screening compound: 3-[1,3-DIETHYL-2-OXO-6-(PYRROLIDIN-1-YL)-2,3-DIHYDRO-1H-1,3-BENZODIAZOL-5-YL]-1-(2,5-DIFLUOROPHENYL)UREA alternative view

Chemical Structure Depiction of ChemDiv screening compound G266-1387
3-[1,3-DIETHYL-2-OXO-6-(PYRROLIDIN-1-YL)-2,3-DIHYDRO-1H-1,3-BENZODIAZOL-5-YL]-1-(2,5-DIFLUOROPHENYL)UREA

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G266-1387

Molecular Formula

C22H25F2N5O2 (C22 H25 F2 N5 O2)

Compound Name

3-[1,3-DIETHYL-2-OXO-6-(PYRROLIDIN-1-YL)-2,3-DIHYDRO-1H-1,3-BENZODIAZOL-5-YL]-1-(2,5-DIFLUOROPHENYL)UREA

IUPAC name

n/a

SMILES

CCN(c(c(N1CC)c2)cc(NC(Nc(cc(cc3)F)c3F)=O)c2N2CCCC2)C1=O

InChI

InChI=1S/C22H25F2N5O2/c1-3-28-19-12-17(26-21(30)25-16-11-14(23)7-8-15(16)24)18(27-9-5-6-10-27)13-20(19)29(4-2)22(28)31/h7-8,11-13H,3-6,9-10H2,1-2H3,(H2,25,26,30)

InChI Key

LHYRYHXGOVLMAQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27212063

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

429.47

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.171

Distribution Coefficient, logD

5.041

Water Solubility, LogSw

-5.08

Polar Surface Area

52.266

Acid Dissociation Constant (pKa)

7.86

Base Dissociation Constant (pKb)

4.42

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

36.40

G266-1387 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Autophagy-Targeted Library (4564 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Infections
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system

References: we are preparing a list of scientific research reports with G266-1387 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G266-1387?
Check Price and Availability of G266-1387, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G266-1387 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G266-1387
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G266-1387
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G266-1387 available by request