G267-0197 Screening compound: 3-[4-(4-fluorophenyl)piperazine-1-carbonyl]-2-methyl-6-[(pyridin-3-yl)methyl]-5,6-dihydro-1,6-naphthyridin-5-one

G267-0197 Screening compound: 3-[4-(4-fluorophenyl)piperazine-1-carbonyl]-2-methyl-6-[(pyridin-3-yl)methyl]-5,6-dihydro-1,6-naphthyridin-5-one
G267-0197 Screening compound: 3-[4-(4-fluorophenyl)piperazine-1-carbonyl]-2-methyl-6-[(pyridin-3-yl)methyl]-5,6-dihydro-1,6-naphthyridin-5-one alternative view

Chemical Structure Depiction of ChemDiv screening compound G267-0197
3-[4-(4-fluorophenyl)piperazine-1-carbonyl]-2-methyl-6-[(pyridin-3-yl)methyl]-5,6-dihydro-1,6-naphthyridin-5-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G267-0197

Molecular Formula

C26H24FN5O2 (C26 H24 FN5 O2)

Compound Name

3-[4-(4-fluorophenyl)piperazine-1-carbonyl]-2-methyl-6-[(pyridin-3-yl)methyl]-5,6-dihydro-1,6-naphthyridin-5-one

IUPAC name

3-[4-(4-fluorophenyl)piperazine-1-carbonyl]-2-methyl-6-[(pyridin-3-yl)methyl]-56-dihydro-16-naphthyridin-5-one

SMILES

Cc(nc(C=CN(Cc1cnccc1)C1=O)c1c1)c1C(N(CC1)CCN1c(cc1)ccc1F)=O

InChI

InChI=1S/C26H24FN5O2/c1-18-22(25(33)31-13-11-30(12-14-31)21-6-4-20(27)5-7-21)15-23-24(29-18)8-10-32(26(23)34)17-19-3-2-9-28-16-19/h2-10,15-16H,11-14,17H2,1H3

InChI Key

CTJGJKZKIAPVTP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14991963

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

457.51

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.414

Distribution Coefficient, logD

2.414

Water Solubility, LogSw

-2.57

Polar Surface Area

55.801

Acid Dissociation Constant (pKa)

25.78

Base Dissociation Constant (pKb)

3.19

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

23.10

G267-0197 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Antiviral Annotated Library (21441 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer

References: we are preparing a list of scientific research reports with G267-0197 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G267-0197?
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What is the minimum amount of G267-0197 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G267-0197
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G267-0197
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G267-0197 available by request