G267-0228 Screening compound: N-(4-acetamidophenyl)-2-methyl-5-oxo-6-[(pyridin-3-yl)methyl]-5,6-dihydro-1,6-naphthyridine-3-carboxamide

G267-0228 Screening compound: N-(4-acetamidophenyl)-2-methyl-5-oxo-6-[(pyridin-3-yl)methyl]-5,6-dihydro-1,6-naphthyridine-3-carboxamide
G267-0228 Screening compound: N-(4-acetamidophenyl)-2-methyl-5-oxo-6-[(pyridin-3-yl)methyl]-5,6-dihydro-1,6-naphthyridine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G267-0228
N-(4-acetamidophenyl)-2-methyl-5-oxo-6-[(pyridin-3-yl)methyl]-5,6-dihydro-1,6-naphthyridine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G267-0228

Molecular Formula

C24H21N5O3 (C24 H21 N5 O3)

Compound Name

N-(4-acetamidophenyl)-2-methyl-5-oxo-6-[(pyridin-3-yl)methyl]-5,6-dihydro-1,6-naphthyridine-3-carboxamide

IUPAC name

N-(4-acetamidophenyl)-2-methyl-5-oxo-6-[(pyridin-3-yl)methyl]-56-dihydro-16-naphthyridine-3-carboxamide

SMILES

CC(Nc(cc1)ccc1NC(c1cc(C(N(Cc2cnccc2)C=C2)=O)c2nc1C)=O)=O

InChI

InChI=1S/C24H21N5O3/c1-15-20(23(31)28-19-7-5-18(6-8-19)27-16(2)30)12-21-22(26-15)9-11-29(24(21)32)14-17-4-3-10-25-13-17/h3-13H,14H2,1-2H3,(H,27,30)(H,28,31)

InChI Key

PUZKBQAYQKZBSI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14991983

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

427.46

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.607

Distribution Coefficient, logD

1.599

Water Solubility, LogSw

-1.92

Polar Surface Area

82.246

Acid Dissociation Constant (pKa)

9.17

Base Dissociation Constant (pKb)

2.51

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

12.50

G267-0228 in Drug Discovery

Included in Screening Libraries

3D-Biodiversity Library (27607 compounds)

Anticancer Library (62698 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Epigenetics Focused Set (26518 compounds)

Target Identification, Phenotypic Screening library (TIPS) (27612 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Cancer

References: we are preparing a list of scientific research reports with G267-0228 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G267-0228?
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What is the minimum amount of G267-0228 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G267-0228
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G267-0228
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G267-0228 available by request