G267-0475 Screening compound: 3-[4-(4-fluorophenyl)piperazine-1-carbonyl]-6-[(furan-2-yl)methyl]-2-methyl-5,6-dihydro-1,6-naphthyridin-5-one

G267-0475 Screening compound: 3-[4-(4-fluorophenyl)piperazine-1-carbonyl]-6-[(furan-2-yl)methyl]-2-methyl-5,6-dihydro-1,6-naphthyridin-5-one
G267-0475 Screening compound: 3-[4-(4-fluorophenyl)piperazine-1-carbonyl]-6-[(furan-2-yl)methyl]-2-methyl-5,6-dihydro-1,6-naphthyridin-5-one alternative view

Chemical Structure Depiction of ChemDiv screening compound G267-0475
3-[4-(4-fluorophenyl)piperazine-1-carbonyl]-6-[(furan-2-yl)methyl]-2-methyl-5,6-dihydro-1,6-naphthyridin-5-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G267-0475

Molecular Formula

C25H23FN4O3 (C25 H23 FN4 O3)

Compound Name

3-[4-(4-fluorophenyl)piperazine-1-carbonyl]-6-[(furan-2-yl)methyl]-2-methyl-5,6-dihydro-1,6-naphthyridin-5-one

IUPAC name

3-[4-(4-fluorophenyl)piperazine-1-carbonyl]-6-[(furan-2-yl)methyl]-2-methyl-56-dihydro-16-naphthyridin-5-one

SMILES

Cc(nc(C=CN(Cc1ccco1)C1=O)c1c1)c1C(N(CC1)CCN1c(cc1)ccc1F)=O

InChI

InChI=1S/C25H23FN4O3/c1-17-21(24(31)29-12-10-28(11-13-29)19-6-4-18(26)5-7-19)15-22-23(27-17)8-9-30(25(22)32)16-20-3-2-14-33-20/h2-9,14-15H,10-13,16H2,1H3

InChI Key

FQYQVMVGLILNQB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14992084

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

446.48

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.296

Distribution Coefficient, logD

3.296

Water Solubility, LogSw

-3.50

Polar Surface Area

54.032

Acid Dissociation Constant (pKa)

28.00

Base Dissociation Constant (pKb)

3.19

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

24.00

G267-0475 in Drug Discovery

Included in Screening Libraries

Human Kinases Annotated Library (2415 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with G267-0475 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G267-0475?
Check Price and Availability of G267-0475, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G267-0475 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G267-0475
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G267-0475
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G267-0475 available by request