G267-0746 Screening compound: 3-{3,5-dimethyl-1-[6-(pyrrolidin-1-yl)pyridazin-3-yl]-1H-pyrazol-4-yl}-1-[4-(pyridin-2-yl)piperazin-1-yl]propan-1-one

G267-0746 Screening compound: 3-{3,5-dimethyl-1-[6-(pyrrolidin-1-yl)pyridazin-3-yl]-1H-pyrazol-4-yl}-1-[4-(pyridin-2-yl)piperazin-1-yl]propan-1-one
G267-0746 Screening compound: 3-{3,5-dimethyl-1-[6-(pyrrolidin-1-yl)pyridazin-3-yl]-1H-pyrazol-4-yl}-1-[4-(pyridin-2-yl)piperazin-1-yl]propan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound G267-0746
3-{3,5-dimethyl-1-[6-(pyrrolidin-1-yl)pyridazin-3-yl]-1H-pyrazol-4-yl}-1-[4-(pyridin-2-yl)piperazin-1-yl]propan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G267-0746

Molecular Formula

C25H32N8O (C25 H32 N8 O)

Compound Name

3-{3,5-dimethyl-1-[6-(pyrrolidin-1-yl)pyridazin-3-yl]-1H-pyrazol-4-yl}-1-[4-(pyridin-2-yl)piperazin-1-yl]propan-1-one

IUPAC name

3-{35-dimethyl-1-[6-(pyrrolidin-1-yl)pyridazin-3-yl]-1H-pyrazol-4-yl}-1-[4-(pyridin-2-yl)piperazin-1-yl]propan-1-one

SMILES

Cc1c(CCC(N(CC2)CCN2c2ncccc2)=O)c(C)nn1-c(cc1)nnc1N1CCCC1

InChI

InChI=1S/C25H32N8O/c1-19-21(8-11-25(34)32-17-15-31(16-18-32)22-7-3-4-12-26-22)20(2)33(29-19)24-10-9-23(27-28-24)30-13-5-6-14-30/h3-4,7,9-10,12H,5-6,8,11,13-18H2,1-2H3

InChI Key

PLGAUOPLGJPHQT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14992236

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

460.58

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.788

Distribution Coefficient, logD

2.736

Water Solubility, LogSw

-2.90

Polar Surface Area

67.037

Acid Dissociation Constant (pKa)

20.94

Base Dissociation Constant (pKb)

6.51

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

48.00

G267-0746 in Drug Discovery

Included in Screening Libraries

SmartTM Library (51161 compounds)

Targeted Diversity Library (40567 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with G267-0746 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G267-0746?
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What is the minimum amount of G267-0746 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G267-0746
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G267-0746
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G267-0746 available by request