G267-0771 Screening compound: 3-{3,5-dimethyl-1-[6-(pyrrolidin-1-yl)pyridazin-3-yl]-1H-pyrazol-4-yl}-N-[4-(trifluoromethoxy)phenyl]propanamide

G267-0771 Screening compound: 3-{3,5-dimethyl-1-[6-(pyrrolidin-1-yl)pyridazin-3-yl]-1H-pyrazol-4-yl}-N-[4-(trifluoromethoxy)phenyl]propanamide
G267-0771 Screening compound: 3-{3,5-dimethyl-1-[6-(pyrrolidin-1-yl)pyridazin-3-yl]-1H-pyrazol-4-yl}-N-[4-(trifluoromethoxy)phenyl]propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G267-0771
3-{3,5-dimethyl-1-[6-(pyrrolidin-1-yl)pyridazin-3-yl]-1H-pyrazol-4-yl}-N-[4-(trifluoromethoxy)phenyl]propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G267-0771

Molecular Formula

C23H25F3N6O2 (C23 H25 F3 N6 O2)

Compound Name

3-{3,5-dimethyl-1-[6-(pyrrolidin-1-yl)pyridazin-3-yl]-1H-pyrazol-4-yl}-N-[4-(trifluoromethoxy)phenyl]propanamide

IUPAC name

3-{35-dimethyl-1-[6-(pyrrolidin-1-yl)pyridazin-3-yl]-1H-pyrazol-4-yl}-N-[4-(trifluoromethoxy)phenyl]propanamide

SMILES

Cc1c(CCC(Nc(cc2)ccc2OC(F)(F)F)=O)c(C)nn1-c(cc1)nnc1N1CCCC1

InChI

InChI=1S/C23H25F3N6O2/c1-15-19(9-12-22(33)27-17-5-7-18(8-6-17)34-23(24,25)26)16(2)32(30-15)21-11-10-20(28-29-21)31-13-3-4-14-31/h5-8,10-11H,3-4,9,12-14H2,1-2H3,(H,27,33)

InChI Key

IWJMNDVTDXDHEM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14992248

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

474.49

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.383

Distribution Coefficient, logD

4.331

Water Solubility, LogSw

-4.22

Polar Surface Area

67.959

Acid Dissociation Constant (pKa)

12.06

Base Dissociation Constant (pKb)

6.51

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

39.10

G267-0771 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Agro:
  • Agro

References: we are preparing a list of scientific research reports with G267-0771 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G267-0771?
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What is the minimum amount of G267-0771 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G267-0771
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G267-0771
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G267-0771 available by request