G267-1054 Screening compound: 3-{3,5-dimethyl-1-[6-(morpholin-4-yl)pyridazin-3-yl]-1H-pyrazol-4-yl}-N-[(pyridin-3-yl)methyl]propanamide

G267-1054 Screening compound: 3-{3,5-dimethyl-1-[6-(morpholin-4-yl)pyridazin-3-yl]-1H-pyrazol-4-yl}-N-[(pyridin-3-yl)methyl]propanamide
G267-1054 Screening compound: 3-{3,5-dimethyl-1-[6-(morpholin-4-yl)pyridazin-3-yl]-1H-pyrazol-4-yl}-N-[(pyridin-3-yl)methyl]propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G267-1054
3-{3,5-dimethyl-1-[6-(morpholin-4-yl)pyridazin-3-yl]-1H-pyrazol-4-yl}-N-[(pyridin-3-yl)methyl]propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G267-1054

Molecular Formula

C22H27N7O2 (C22 H27 N7 O2)

Compound Name

3-{3,5-dimethyl-1-[6-(morpholin-4-yl)pyridazin-3-yl]-1H-pyrazol-4-yl}-N-[(pyridin-3-yl)methyl]propanamide

IUPAC name

3-{35-dimethyl-1-[6-(morpholin-4-yl)pyridazin-3-yl]-1H-pyrazol-4-yl}-N-[(pyridin-3-yl)methyl]propanamide

SMILES

Cc1c(CCC(NCc2cnccc2)=O)c(C)nn1-c(cc1)nnc1N1CCOCC1

InChI

InChI=1S/C22H27N7O2/c1-16-19(5-8-22(30)24-15-18-4-3-9-23-14-18)17(2)29(27-16)21-7-6-20(25-26-21)28-10-12-31-13-11-28/h3-4,6-7,9,14H,5,8,10-13,15H2,1-2H3,(H,24,30)

InChI Key

FXBRCBDJNPAECR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14992435

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

421.5

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

0.941

Distribution Coefficient, logD

0.870

Water Solubility, LogSw

-0.97

Polar Surface Area

80.405

Acid Dissociation Constant (pKa)

13.67

Base Dissociation Constant (pKb)

6.65

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.90

G267-1054 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

PI3K-Targeted Library (17255 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • GPCR
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G267-1054 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G267-1054?
Check Price and Availability of G267-1054, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G267-1054 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G267-1054
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G267-1054
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G267-1054 available by request