G267-1226 Screening compound: 6-benzyl-2-methyl-5-oxo-N-{[4-(propan-2-yloxy)phenyl]methyl}-5,6-dihydro-1,6-naphthyridine-3-carboxamide

G267-1226 Screening compound: 6-benzyl-2-methyl-5-oxo-N-{[4-(propan-2-yloxy)phenyl]methyl}-5,6-dihydro-1,6-naphthyridine-3-carboxamide
G267-1226 Screening compound: 6-benzyl-2-methyl-5-oxo-N-{[4-(propan-2-yloxy)phenyl]methyl}-5,6-dihydro-1,6-naphthyridine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G267-1226
6-benzyl-2-methyl-5-oxo-N-{[4-(propan-2-yloxy)phenyl]methyl}-5,6-dihydro-1,6-naphthyridine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G267-1226

Molecular Formula

C27H27N3O3 (C27 H27 N3 O3)

Compound Name

6-benzyl-2-methyl-5-oxo-N-{[4-(propan-2-yloxy)phenyl]methyl}-5,6-dihydro-1,6-naphthyridine-3-carboxamide

IUPAC name

6-benzyl-2-methyl-5-oxo-N-{[4-(propan-2-yloxy)phenyl]methyl}-56-dihydro-16-naphthyridine-3-carboxamide

SMILES

CC(C)Oc1ccc(CNC(c2cc(C(N(Cc3ccccc3)C=C3)=O)c3nc2C)=O)cc1

InChI

InChI=1S/C27H27N3O3/c1-18(2)33-22-11-9-20(10-12-22)16-28-26(31)23-15-24-25(29-19(23)3)13-14-30(27(24)32)17-21-7-5-4-6-8-21/h4-15,18H,16-17H2,1-3H3,(H,28,31)

InChI Key

ZSITXRRDUHIERS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14992513

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

441.53

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.349

Distribution Coefficient, logD

4.349

Water Solubility, LogSw

-4.35

Polar Surface Area

57.591

Acid Dissociation Constant (pKa)

10.77

Base Dissociation Constant (pKb)

3.37

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

22.20

G267-1226 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with G267-1226 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G267-1226?
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What is the minimum amount of G267-1226 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G267-1226
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G267-1226
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G267-1226 available by request