G271-0188 Screening compound: 2-[4-(1-pyrrolidinylsulfonyl)-1H-imidazol-1-yl]-N-[4-(trifluoromethoxy)phenyl]acetamide

G271-0188 Screening compound: 2-[4-(1-pyrrolidinylsulfonyl)-1H-imidazol-1-yl]-N-[4-(trifluoromethoxy)phenyl]acetamide
G271-0188 Screening compound: 2-[4-(1-pyrrolidinylsulfonyl)-1H-imidazol-1-yl]-N-[4-(trifluoromethoxy)phenyl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G271-0188
2-[4-(1-pyrrolidinylsulfonyl)-1H-imidazol-1-yl]-N-[4-(trifluoromethoxy)phenyl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G271-0188

Molecular Formula

C16H17F3N4O4S (C16 H17 F3 N4 O4 S)

Compound Name

2-[4-(1-pyrrolidinylsulfonyl)-1H-imidazol-1-yl]-N-[4-(trifluoromethoxy)phenyl]acetamide

IUPAC name

2-[4-(pyrrolidine-1-sulfonyl)-1H-imidazol-1-yl]-N-[4-(trifluoromethoxy)phenyl]acetamide

SMILES

O=C(Cn1cnc(S(N2CCCC2)(=O)=O)c1)Nc(cc1)ccc1OC(F)(F)F

InChI

InChI=1S/C16H17F3N4O4S/c17-16(18,19)27-13-5-3-12(4-6-13)21-14(24)9-22-10-15(20-11-22)28(25,26)23-7-1-2-8-23/h3-6,10-11H,1-2,7-9H2,(H,21,24)

InChI Key

JGNOXUZRAISGPL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14992676

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

418.4

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.629

Distribution Coefficient, logD

2.629

Water Solubility, LogSw

-3.08

Polar Surface Area

73.240

Acid Dissociation Constant (pKa)

12.15

Base Dissociation Constant (pKb)

2.18

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

37.50

G271-0188 in Drug Discovery

Included in Screening Libraries

3D-Biodiversity Library (27607 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS targets activity set (6557 compounds)

Human GPCR Annotated Library (5539 compounds)

Selective Target Activity Profiling Library (14702 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

New Agro Library (44492 compounds)

Target Identification, Phenotypic Screening library (TIPS) (27612 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Agro:
  • Agro

References: we are preparing a list of scientific research reports with G271-0188 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G271-0188?
Check Price and Availability of G271-0188, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G271-0188 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G271-0188
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G271-0188
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G271-0188 available by request