G274-0317 Screening compound: N-[3-(1,2,3,4-tetrahydroquinolin-1-yl)propyl]-1-[6-(thiophen-2-yl)pyridazin-3-yl]piperidine-4-carboxamide

G274-0317 Screening compound: N-[3-(1,2,3,4-tetrahydroquinolin-1-yl)propyl]-1-[6-(thiophen-2-yl)pyridazin-3-yl]piperidine-4-carboxamide
G274-0317 Screening compound: N-[3-(1,2,3,4-tetrahydroquinolin-1-yl)propyl]-1-[6-(thiophen-2-yl)pyridazin-3-yl]piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G274-0317
N-[3-(1,2,3,4-tetrahydroquinolin-1-yl)propyl]-1-[6-(thiophen-2-yl)pyridazin-3-yl]piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G274-0317

Molecular Formula

C26H31N5OS (C26 H31 N5 OS)

Compound Name

N-[3-(1,2,3,4-tetrahydroquinolin-1-yl)propyl]-1-[6-(thiophen-2-yl)pyridazin-3-yl]piperidine-4-carboxamide

IUPAC name

N-[3-(1234-tetrahydroquinolin-1-yl)propyl]-1-[6-(thiophen-2-yl)pyridazin-3-yl]piperidine-4-carboxamide

SMILES

O=C(C(CC1)CCN1c(cc1)nnc1-c1cccs1)NCCCN(CCC1)c2c1cccc2

InChI

InChI=1S/C26H31N5OS/c32-26(27-14-5-16-30-15-3-7-20-6-1-2-8-23(20)30)21-12-17-31(18-13-21)25-11-10-22(28-29-25)24-9-4-19-33-24/h1-2,4,6,8-11,19,21H,3,5,7,12-18H2,(H,27,32)

InChI Key

IGSNDMGJTDRYJU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14992906

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

461.63

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.314

Distribution Coefficient, logD

4.258

Water Solubility, LogSw

-4.19

Polar Surface Area

52.712

Acid Dissociation Constant (pKa)

14.50

Base Dissociation Constant (pKb)

7.77

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

42.30

G274-0317 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G274-0317 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G274-0317?
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What is the minimum amount of G274-0317 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G274-0317
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G274-0317
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G274-0317 available by request