G274-1007 Screening compound: 3-(5-bromothiophen-2-yl)-6-{4-[4-(pyridin-2-yl)piperazine-1-carbonyl]piperidin-1-yl}pyridazine

G274-1007 Screening compound: 3-(5-bromothiophen-2-yl)-6-{4-[4-(pyridin-2-yl)piperazine-1-carbonyl]piperidin-1-yl}pyridazine
G274-1007 Screening compound: 3-(5-bromothiophen-2-yl)-6-{4-[4-(pyridin-2-yl)piperazine-1-carbonyl]piperidin-1-yl}pyridazine alternative view

Chemical Structure Depiction of ChemDiv screening compound G274-1007
3-(5-bromothiophen-2-yl)-6-{4-[4-(pyridin-2-yl)piperazine-1-carbonyl]piperidin-1-yl}pyridazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G274-1007

Molecular Formula

C23H25BrN6OS (C23 H25 BrN6 OS)

Compound Name

3-(5-bromothiophen-2-yl)-6-{4-[4-(pyridin-2-yl)piperazine-1-carbonyl]piperidin-1-yl}pyridazine

IUPAC name

3-(5-bromothiophen-2-yl)-6-{4-[4-(pyridin-2-yl)piperazine-1-carbonyl]piperidin-1-yl}pyridazine

SMILES

O=C(C(CC1)CCN1c(cc1)nnc1-c(s1)ccc1Br)N(CC1)CCN1c1ncccc1

InChI

InChI=1S/C23H25BrN6OS/c24-20-6-5-19(32-20)18-4-7-22(27-26-18)28-11-8-17(9-12-28)23(31)30-15-13-29(14-16-30)21-3-1-2-10-25-21/h1-7,10,17H,8-9,11-16H2

InChI Key

KYVVRCHBKNXDBR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14992966

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

513.46

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.388

Distribution Coefficient, logD

4.379

Water Solubility, LogSw

-4.30

Polar Surface Area

54.064

Acid Dissociation Constant (pKa)

22.96

Base Dissociation Constant (pKb)

5.71

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

39.10

G274-1007 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular

References: we are preparing a list of scientific research reports with G274-1007 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G274-1007?
Check Price and Availability of G274-1007, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G274-1007 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G274-1007
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G274-1007
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G274-1007 available by request