G275-0955 Screening compound: 8-{[5-(3-methyl-1H-pyrazol-5-yl)thiophen-2-yl]sulfonyl}-1,4-dioxa-8-azaspiro[4.5]decane

G275-0955 Screening compound: 8-{[5-(3-methyl-1H-pyrazol-5-yl)thiophen-2-yl]sulfonyl}-1,4-dioxa-8-azaspiro[4.5]decane
G275-0955 Screening compound: 8-{[5-(3-methyl-1H-pyrazol-5-yl)thiophen-2-yl]sulfonyl}-1,4-dioxa-8-azaspiro[4.5]decane alternative view

Chemical Structure Depiction of ChemDiv screening compound G275-0955
8-{[5-(3-methyl-1H-pyrazol-5-yl)thiophen-2-yl]sulfonyl}-1,4-dioxa-8-azaspiro[4.5]decane

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G275-0955

Molecular Formula

C15H19N3O4S2 (C15 H19 N3 O4 S2)

Compound Name

8-{[5-(3-methyl-1H-pyrazol-5-yl)thiophen-2-yl]sulfonyl}-1,4-dioxa-8-azaspiro[4.5]decane

IUPAC name

8-{[5-(3-methyl-1H-pyrazol-5-yl)thiophen-2-yl]sulfonyl}-14-dioxa-8-azaspiro[4.5]decane

SMILES

Cc1n[nH]c(-c(s2)ccc2S(N(CC2)CCC22OCCO2)(=O)=O)c1

InChI

InChI=1S/C15H19N3O4S2/c1-11-10-12(17-16-11)13-2-3-14(23-13)24(19,20)18-6-4-15(5-7-18)21-8-9-22-15/h2-3,10H,4-9H2,1H3,(H,16,17)

InChI Key

HWAVLVKZGHETSG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14993069

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

369.47

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.120

Distribution Coefficient, logD

2.119

Water Solubility, LogSw

-2.67

Polar Surface Area

69.701

Acid Dissociation Constant (pKa)

8.93

Base Dissociation Constant (pKb)

4.67

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

53.30

G275-0955 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • GPCR
  • Others
  • Kinases
Mechanism of action:
  • Receptor's ligands
  • Epigenetic

References: we are preparing a list of scientific research reports with G275-0955 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G275-0955?
Check Price and Availability of G275-0955, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G275-0955 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G275-0955
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G275-0955
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G275-0955 available by request