G275-1220 Screening compound: 5-(3,4-dimethyl-1H-pyrazol-5-yl)-N-[3-(trifluoromethyl)phenyl]thiophene-2-sulfonamide

G275-1220 Screening compound: 5-(3,4-dimethyl-1H-pyrazol-5-yl)-N-[3-(trifluoromethyl)phenyl]thiophene-2-sulfonamide
G275-1220 Screening compound: 5-(3,4-dimethyl-1H-pyrazol-5-yl)-N-[3-(trifluoromethyl)phenyl]thiophene-2-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G275-1220
5-(3,4-dimethyl-1H-pyrazol-5-yl)-N-[3-(trifluoromethyl)phenyl]thiophene-2-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G275-1220

Molecular Formula

C16H14F3N3O2S2 (C16 H14 F3 N3 O2 S2)

Compound Name

5-(3,4-dimethyl-1H-pyrazol-5-yl)-N-[3-(trifluoromethyl)phenyl]thiophene-2-sulfonamide

IUPAC name

5-(34-dimethyl-1H-pyrazol-5-yl)-N-[3-(trifluoromethyl)phenyl]thiophene-2-sulfonamide

SMILES

Cc1c(-c(s2)ccc2S(Nc2cc(C(F)(F)F)ccc2)(=O)=O)[nH]nc1C

InChI

InChI=1S/C16H14F3N3O2S2/c1-9-10(2)20-21-15(9)13-6-7-14(25-13)26(23,24)22-12-5-3-4-11(8-12)16(17,18)19/h3-8,22H,1-2H3,(H,20,21)

InChI Key

HGFZOUDSSBWGJS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14993107

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

401.43

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.738

Distribution Coefficient, logD

4.121

Water Solubility, LogSw

-4.59

Polar Surface Area

65.743

Acid Dissociation Constant (pKa)

6.90

Base Dissociation Constant (pKb)

5.37

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

18.80

G275-1220 in Drug Discovery

Included in Screening Libraries

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cardiovascular
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with G275-1220 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G275-1220?
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What is the minimum amount of G275-1220 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G275-1220
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G275-1220
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G275-1220 available by request