G275-1346 Screening compound: 1-{[5-(3,4-dimethyl-1H-pyrazol-5-yl)thiophen-2-yl]sulfonyl}-4-(pyridin-2-yl)piperazine

G275-1346 Screening compound: 1-{[5-(3,4-dimethyl-1H-pyrazol-5-yl)thiophen-2-yl]sulfonyl}-4-(pyridin-2-yl)piperazine
G275-1346 Screening compound: 1-{[5-(3,4-dimethyl-1H-pyrazol-5-yl)thiophen-2-yl]sulfonyl}-4-(pyridin-2-yl)piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound G275-1346
1-{[5-(3,4-dimethyl-1H-pyrazol-5-yl)thiophen-2-yl]sulfonyl}-4-(pyridin-2-yl)piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G275-1346

Molecular Formula

C18H21N5O2S2 (C18 H21 N5 O2 S2)

Compound Name

1-{[5-(3,4-dimethyl-1H-pyrazol-5-yl)thiophen-2-yl]sulfonyl}-4-(pyridin-2-yl)piperazine

IUPAC name

1-{[5-(34-dimethyl-1H-pyrazol-5-yl)thiophen-2-yl]sulfonyl}-4-(pyridin-2-yl)piperazine

SMILES

Cc1c(-c(s2)ccc2S(N(CC2)CCN2c2ncccc2)(=O)=O)[nH]nc1C

InChI

InChI=1S/C18H21N5O2S2/c1-13-14(2)20-21-18(13)15-6-7-17(26-15)27(24,25)23-11-9-22(10-12-23)16-5-3-4-8-19-16/h3-8H,9-12H2,1-2H3,(H,20,21)

InChI Key

UBMPVYAEEVIZRY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14993163

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

403.53

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.282

Distribution Coefficient, logD

3.257

Water Solubility, LogSw

-3.48

Polar Surface Area

68.576

Acid Dissociation Constant (pKa)

9.17

Base Dissociation Constant (pKb)

6.16

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

G275-1346 in Drug Discovery

Included in Screening Libraries

SmartTM Library (51161 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with G275-1346 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G275-1346?
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What is the minimum amount of G275-1346 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G275-1346
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G275-1346
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G275-1346 available by request