G275-2265 Screening compound: N-(2-chloro-4,6-dimethoxyphenyl)-5-(1H-pyrazol-5-yl)thiophene-2-sulfonamide

G275-2265 Screening compound: N-(2-chloro-4,6-dimethoxyphenyl)-5-(1H-pyrazol-5-yl)thiophene-2-sulfonamide
G275-2265 Screening compound: N-(2-chloro-4,6-dimethoxyphenyl)-5-(1H-pyrazol-5-yl)thiophene-2-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G275-2265
N-(2-chloro-4,6-dimethoxyphenyl)-5-(1H-pyrazol-5-yl)thiophene-2-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G275-2265

Molecular Formula

C15H14ClN3O4S2 (C15 H14 ClN3 O4 S2)

Compound Name

N-(2-chloro-4,6-dimethoxyphenyl)-5-(1H-pyrazol-5-yl)thiophene-2-sulfonamide

IUPAC name

N-(2-chloro-46-dimethoxyphenyl)-5-(1H-pyrazol-5-yl)thiophene-2-sulfonamide

SMILES

COc(cc1OC)cc(Cl)c1NS(c1ccc(-c2ccn[nH]2)s1)(=O)=O

InChI

InChI=1S/C15H14ClN3O4S2/c1-22-9-7-10(16)15(12(8-9)23-2)19-25(20,21)14-4-3-13(24-14)11-5-6-17-18-11/h3-8,19H,1-2H3,(H,17,18)

InChI Key

URMKKVGVOXCJMU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27212467

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

399.88

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.179

Distribution Coefficient, logD

1.424

Water Solubility, LogSw

-3.61

Polar Surface Area

79.015

Acid Dissociation Constant (pKa)

5.65

Base Dissociation Constant (pKb)

3.94

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

13.30

G275-2265 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with G275-2265 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G275-2265?
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What is the minimum amount of G275-2265 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G275-2265
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G275-2265
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G275-2265 available by request