G278-0298 Screening compound: 5-(2,3-DIHYDRO-4H-1,4-BENZOXAZIN-4-YL)-N-(2,5-DIMETHOXYBENZYL)-2-THIOPHENECARBOXAMIDE

G278-0298 Screening compound: 5-(2,3-DIHYDRO-4H-1,4-BENZOXAZIN-4-YL)-N-(2,5-DIMETHOXYBENZYL)-2-THIOPHENECARBOXAMIDE
G278-0298 Screening compound: 5-(2,3-DIHYDRO-4H-1,4-BENZOXAZIN-4-YL)-N-(2,5-DIMETHOXYBENZYL)-2-THIOPHENECARBOXAMIDE alternative view

Chemical Structure Depiction of ChemDiv screening compound G278-0298
5-(2,3-DIHYDRO-4H-1,4-BENZOXAZIN-4-YL)-N-(2,5-DIMETHOXYBENZYL)-2-THIOPHENECARBOXAMIDE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G278-0298

Molecular Formula

C22H22N2O4S (C22 H22 N2 O4 S)

Compound Name

5-(2,3-DIHYDRO-4H-1,4-BENZOXAZIN-4-YL)-N-(2,5-DIMETHOXYBENZYL)-2-THIOPHENECARBOXAMIDE

IUPAC name

n/a

SMILES

COc(cc1)cc(CNC(c2ccc(N3c(cccc4)c4OCC3)s2)=O)c1OC

InChI

InChI=1S/C22H22N2O4S/c1-26-16-7-8-18(27-2)15(13-16)14-23-22(25)20-9-10-21(29-20)24-11-12-28-19-6-4-3-5-17(19)24/h3-10,13H,11-12,14H2,1-2H3,(H,23,25)

InChI Key

BBVUKMJWIMGXBI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14993241

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

410.49

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.586

Distribution Coefficient, logD

4.586

Water Solubility, LogSw

-4.30

Polar Surface Area

51.264

Acid Dissociation Constant (pKa)

13.79

Base Dissociation Constant (pKb)

-0.25

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

22.70

G278-0298 in Drug Discovery

Included in Screening Libraries

PI3K-Targeted Library (17255 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with G278-0298 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G278-0298?
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What is the minimum amount of G278-0298 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G278-0298
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G278-0298
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G278-0298 available by request