G279-0105 Screening compound: N-(1-benzyl-4-piperidyl)-2-[3-methyl-5-oxo-1-phenyl-5,6-dihydropyrazolo[3,4-b][1,4]thiazin-4(1H)-yl]acetamide

G279-0105 Screening compound: N-(1-benzyl-4-piperidyl)-2-[3-methyl-5-oxo-1-phenyl-5,6-dihydropyrazolo[3,4-b][1,4]thiazin-4(1H)-yl]acetamide
G279-0105 Screening compound: N-(1-benzyl-4-piperidyl)-2-[3-methyl-5-oxo-1-phenyl-5,6-dihydropyrazolo[3,4-b][1,4]thiazin-4(1H)-yl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G279-0105
N-(1-benzyl-4-piperidyl)-2-[3-methyl-5-oxo-1-phenyl-5,6-dihydropyrazolo[3,4-b][1,4]thiazin-4(1H)-yl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G279-0105

Molecular Formula

C26H29N5O2S (C26 H29 N5 O2 S)

Compound Name

N-(1-benzyl-4-piperidyl)-2-[3-methyl-5-oxo-1-phenyl-5,6-dihydropyrazolo[3,4-b][1,4]thiazin-4(1H)-yl]acetamide

IUPAC name

n/a

SMILES

Cc(c(N1CC(NC2CCN(Cc3ccccc3)CC2)=O)c2SCC1=O)nn2-c1ccccc1

InChI

InChI=1S/C26H29N5O2S/c1-19-25-26(31(28-19)22-10-6-3-7-11-22)34-18-24(33)30(25)17-23(32)27-21-12-14-29(15-13-21)16-20-8-4-2-5-9-20/h2-11,21H,12-18H2,1H3,(H,27,32)

InChI Key

KZDSRNGAQCKANT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14993323

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

475.61

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.614

Distribution Coefficient, logD

1.056

Water Solubility, LogSw

-2.81

Polar Surface Area

57.305

Acid Dissociation Constant (pKa)

16.08

Base Dissociation Constant (pKb)

8.95

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

34.62

G279-0105 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Protein-Protein Interaction Library (218420 compounds)

Targeted Diversity Library (40567 compounds)

Anti-HIV1 Library (19540 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Hemic and lymphatic
  • Cardiovascular
  • Antiviral
  • Infections
  • Immune system
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • PPI modulators

References: we are preparing a list of scientific research reports with G279-0105 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G279-0105?
Check Price and Availability of G279-0105, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G279-0105 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G279-0105
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G279-0105
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G279-0105 available by request