G280-0406 Screening compound: ethyl 4-{4-[(2,3,4-trimethoxyphenyl)methyl]piperazin-1-yl}-[1,2]oxazolo[5,4-d]pyrimidine-3-carboxylate

G280-0406 Screening compound: ethyl 4-{4-[(2,3,4-trimethoxyphenyl)methyl]piperazin-1-yl}-[1,2]oxazolo[5,4-d]pyrimidine-3-carboxylate
G280-0406 Screening compound: ethyl 4-{4-[(2,3,4-trimethoxyphenyl)methyl]piperazin-1-yl}-[1,2]oxazolo[5,4-d]pyrimidine-3-carboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound G280-0406
ethyl 4-{4-[(2,3,4-trimethoxyphenyl)methyl]piperazin-1-yl}-[1,2]oxazolo[5,4-d]pyrimidine-3-carboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G280-0406

Molecular Formula

C22H27N5O6 (C22 H27 N5 O6)

Compound Name

ethyl 4-{4-[(2,3,4-trimethoxyphenyl)methyl]piperazin-1-yl}-[1,2]oxazolo[5,4-d]pyrimidine-3-carboxylate

IUPAC name

ethyl 4-{4-[(234-trimethoxyphenyl)methyl]piperazin-1-yl}-[12]oxazolo[54-d]pyrimidine-3-carboxylate

SMILES

CCOC(c1noc2ncnc(N3CCN(Cc(ccc(OC)c4OC)c4OC)CC3)c12)=O

InChI

InChI=1S/C22H27N5O6/c1-5-32-22(28)17-16-20(23-13-24-21(16)33-25-17)27-10-8-26(9-11-27)12-14-6-7-15(29-2)19(31-4)18(14)30-3/h6-7,13H,5,8-12H2,1-4H3

InChI Key

LMAVZEREEZLYCN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14993586

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

457.49

Hydrogen Bond Acceptors Count

11.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

11

Partition Coefficient, logP

2.572

Distribution Coefficient, logD

1.949

Water Solubility, LogSw

-2.71

Polar Surface Area

93.165

Acid Dissociation Constant (pKa)

21.11

Base Dissociation Constant (pKb)

7.90

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

45.50

G280-0406 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with G280-0406 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G280-0406?
Check Price and Availability of G280-0406, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G280-0406 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G280-0406
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G280-0406
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G280-0406 available by request