G281-2940 Screening compound: 9-ethyl-N~5~-(4-methylphenyl)-4-phenyl-7,8,9,10-tetrahydro-4H-pyrido[4',3':4,5]thieno[3,2-f]pyrrolo[1,2-a][1,4]diazepine-5(6H)-carboxamide

G281-2940 Screening compound: 9-ethyl-N~5~-(4-methylphenyl)-4-phenyl-7,8,9,10-tetrahydro-4H-pyrido[4',3':4,5]thieno[3,2-f]pyrrolo[1,2-a][1,4]diazepine-5(6H)-carboxamide
G281-2940 Screening compound: 9-ethyl-N~5~-(4-methylphenyl)-4-phenyl-7,8,9,10-tetrahydro-4H-pyrido[4',3':4,5]thieno[3,2-f]pyrrolo[1,2-a][1,4]diazepine-5(6H)-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G281-2940
9-ethyl-N~5~-(4-methylphenyl)-4-phenyl-7,8,9,10-tetrahydro-4H-pyrido[4',3':4,5]thieno[3,2-f]pyrrolo[1,2-a][1,4]diazepine-5(6H)-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G281-2940

Molecular Formula

C29H30N4OS (C29 H30 N4 OS)

Compound Name

9-ethyl-N~5~-(4-methylphenyl)-4-phenyl-7,8,9,10-tetrahydro-4H-pyrido[4',3':4,5]thieno[3,2-f]pyrrolo[1,2-a][1,4]diazepine-5(6H)-carboxamide

IUPAC name

14-ethyl-N-(4-methylphenyl)-7-phenyl-17-thia-2814-triazatetracyclo[8.7.0.0^{26}.0^{1116}]heptadeca-1(10)3511(16)-tetraene-8-carboxamide

SMILES

CCN(CC1)Cc2c1c(CN(C(c1cccn1-1)c3ccccc3)C(Nc3ccc(C)cc3)=O)c1s2

InChI

InChI=1S/C29H30N4OS/c1-3-31-17-15-23-24-18-33(29(34)30-22-13-11-20(2)12-14-22)27(21-8-5-4-6-9-21)25-10-7-16-32(25)28(24)35-26(23)19-31/h4-14,16,27H,3,15,17-19H2,1-2H3,(H,30,34)/t27-/m0/s1

InChI Key

GJTKIVGHOUVHFF-MHZLTWQESA-N

MDL Number (MFCD)

MFCD27212747

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

482.65

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

6.524

Distribution Coefficient, logD

4.608

Water Solubility, LogSw

-5.66

Polar Surface Area

30.413

Acid Dissociation Constant (pKa)

14.66

Base Dissociation Constant (pKb)

9.31

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

27.60

G281-2940 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Recognition Elements PPI Library (24135 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with G281-2940 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G281-2940?
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What is the minimum amount of G281-2940 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G281-2940
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G281-2940
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G281-2940 available by request