G282-0498 Screening compound: N-benzyl-1-(2,3-dihydro-1H-indol-1-ylcarbonyl)-6-methyl-8-oxo-7-propyl-5,6,7,8-tetrahydroimidazo[1,5-a]pyrazine-6-carboxamide

G282-0498 Screening compound: N-benzyl-1-(2,3-dihydro-1H-indol-1-ylcarbonyl)-6-methyl-8-oxo-7-propyl-5,6,7,8-tetrahydroimidazo[1,5-a]pyrazine-6-carboxamide
G282-0498 Screening compound: N-benzyl-1-(2,3-dihydro-1H-indol-1-ylcarbonyl)-6-methyl-8-oxo-7-propyl-5,6,7,8-tetrahydroimidazo[1,5-a]pyrazine-6-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G282-0498
N-benzyl-1-(2,3-dihydro-1H-indol-1-ylcarbonyl)-6-methyl-8-oxo-7-propyl-5,6,7,8-tetrahydroimidazo[1,5-a]pyrazine-6-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G282-0498

Molecular Formula

C27H29N5O3 (C27 H29 N5 O3)

Compound Name

N-benzyl-1-(2,3-dihydro-1H-indol-1-ylcarbonyl)-6-methyl-8-oxo-7-propyl-5,6,7,8-tetrahydroimidazo[1,5-a]pyrazine-6-carboxamide

IUPAC name

N-benzyl-1-(23-dihydro-1H-indole-1-carbonyl)-6-methyl-8-oxo-7-propyl-5H6H7H8H-imidazo[15-a]pyrazine-6-carboxamide

SMILES

CCCN(C(C)(Cn1c2c(C(N(CC3)c4c3cccc4)=O)nc1)C(NCc1ccccc1)=O)C2=O

InChI

InChI=1S/C27H29N5O3/c1-3-14-32-25(34)23-22(24(33)31-15-13-20-11-7-8-12-21(20)31)29-18-30(23)17-27(32,2)26(35)28-16-19-9-5-4-6-10-19/h4-12,18H,3,13-17H2,1-2H3,(H,28,35)/t27-/m0/s1

InChI Key

KTJXATYPKQWZTD-MHZLTWQESA-N

MDL Number (MFCD)

MFCD27212752

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

471.56

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.825

Distribution Coefficient, logD

2.825

Water Solubility, LogSw

-3.20

Polar Surface Area

67.614

Acid Dissociation Constant (pKa)

12.33

Base Dissociation Constant (pKb)

1.30

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

33.33

G282-0498 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

Anticancer Library (62698 compounds)

Cyclic Ugi PPI Library (9586 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with G282-0498 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G282-0498?
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What is the minimum amount of G282-0498 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G282-0498
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G282-0498
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G282-0498 available by request