G282-0819 Screening compound: 6-methyl-N-(3-methylbenzyl)-N-(4-methylbenzyl)-8-oxo-7-propyl-5,6,7,8-tetrahydroimidazo[1,5-a]pyrazine-1,6-dicarboxamide

G282-0819 Screening compound: 6-methyl-N-(3-methylbenzyl)-N-(4-methylbenzyl)-8-oxo-7-propyl-5,6,7,8-tetrahydroimidazo[1,5-a]pyrazine-1,6-dicarboxamide
G282-0819 Screening compound: 6-methyl-N-(3-methylbenzyl)-N-(4-methylbenzyl)-8-oxo-7-propyl-5,6,7,8-tetrahydroimidazo[1,5-a]pyrazine-1,6-dicarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G282-0819
6-methyl-N-(3-methylbenzyl)-N-(4-methylbenzyl)-8-oxo-7-propyl-5,6,7,8-tetrahydroimidazo[1,5-a]pyrazine-1,6-dicarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G282-0819

Molecular Formula

C28H33N5O3 (C28 H33 N5 O3)

Compound Name

6-methyl-N-(3-methylbenzyl)-N-(4-methylbenzyl)-8-oxo-7-propyl-5,6,7,8-tetrahydroimidazo[1,5-a]pyrazine-1,6-dicarboxamide

IUPAC name

6-methyl-N1-[(3-methylphenyl)methyl]-N6-[(4-methylphenyl)methyl]-8-oxo-7-propyl-5H6H7H8H-imidazo[15-a]pyrazine-16-dicarboxamide

SMILES

CCCN(C(C)(Cn1c2c(C(NCc3cc(C)ccc3)=O)nc1)C(NCc1ccc(C)cc1)=O)C2=O

InChI

InChI=1S/C28H33N5O3/c1-5-13-33-26(35)24-23(25(34)29-16-22-8-6-7-20(3)14-22)31-18-32(24)17-28(33,4)27(36)30-15-21-11-9-19(2)10-12-21/h6-12,14,18H,5,13,15-17H2,1-4H3,(H,29,34)(H,30,36)/t28-/m0/s1

InChI Key

TUJFIOKWCLYWMH-NDEPHWFRSA-N

MDL Number (MFCD)

MFCD27212791

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

487.6

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.553

Distribution Coefficient, logD

3.553

Water Solubility, LogSw

-3.53

Polar Surface Area

76.348

Acid Dissociation Constant (pKa)

12.33

Base Dissociation Constant (pKb)

0.16

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

35.71

G282-0819 in Drug Discovery

Included in Screening Libraries

Cyclic Ugi PPI Library (9586 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Protein-Protein Interaction Library (218420 compounds)

Antibacterial Compounds Library (13827 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
  • Mimetics
  • Mimetics
  • Mimetics
Therapeutical areas:
  • Infections
  • Immune system
  • animal

References: we are preparing a list of scientific research reports with G282-0819 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G282-0819?
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What is the minimum amount of G282-0819 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G282-0819
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G282-0819
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G282-0819 available by request