G282-1863 Screening compound: N-[(4-fluorophenyl)methyl]-6-methyl-8-oxo-1-(4-phenylpiperazine-1-carbonyl)-7-propyl-5H,6H,7H,8H-imidazo[1,5-a]pyrazine-6-carboxamide

G282-1863 Screening compound: N-[(4-fluorophenyl)methyl]-6-methyl-8-oxo-1-(4-phenylpiperazine-1-carbonyl)-7-propyl-5H,6H,7H,8H-imidazo[1,5-a]pyrazine-6-carboxamide
G282-1863 Screening compound: N-[(4-fluorophenyl)methyl]-6-methyl-8-oxo-1-(4-phenylpiperazine-1-carbonyl)-7-propyl-5H,6H,7H,8H-imidazo[1,5-a]pyrazine-6-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G282-1863
N-[(4-fluorophenyl)methyl]-6-methyl-8-oxo-1-(4-phenylpiperazine-1-carbonyl)-7-propyl-5H,6H,7H,8H-imidazo[1,5-a]pyrazine-6-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G282-1863

Molecular Formula

C29H33FN6O3 (C29 H33 FN6 O3)

Compound Name

N-[(4-fluorophenyl)methyl]-6-methyl-8-oxo-1-(4-phenylpiperazine-1-carbonyl)-7-propyl-5H,6H,7H,8H-imidazo[1,5-a]pyrazine-6-carboxamide

IUPAC name

N-[(4-fluorophenyl)methyl]-6-methyl-8-oxo-1-(4-phenylpiperazine-1-carbonyl)-7-propyl-5H6H7H8H-imidazo[15-a]pyrazine-6-carboxamide

SMILES

CCCN(C(C)(Cn1c2c(C(N(CC3)CCN3c3ccccc3)=O)nc1)C(NCc(cc1)ccc1F)=O)C2=O

InChI

InChI=1S/C29H33FN6O3/c1-3-13-36-27(38)25-24(26(37)34-16-14-33(15-17-34)23-7-5-4-6-8-23)32-20-35(25)19-29(36,2)28(39)31-18-21-9-11-22(30)12-10-21/h4-12,20H,3,13-19H2,1-2H3,(H,31,39)/t29-/m0/s1

InChI Key

PDQPAKMSLVCUAX-LJAQVGFWSA-N

MDL Number (MFCD)

MFCD27212825

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

532.62

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.665

Distribution Coefficient, logD

2.665

Water Solubility, LogSw

-2.75

Polar Surface Area

71.843

Acid Dissociation Constant (pKa)

11.91

Base Dissociation Constant (pKb)

2.68

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

37.90

G282-1863 in Drug Discovery

Included in Screening Libraries

Cyclic Ugi PPI Library (9586 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Protein-Protein Interaction Library (218420 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
  • Mimetics
  • Mimetics
  • Mimetics

References: we are preparing a list of scientific research reports with G282-1863 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G282-1863?
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What is the minimum amount of G282-1863 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G282-1863
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G282-1863
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G282-1863 available by request