G282-1948 Screening compound: N6-[(4-fluorophenyl)methyl]-6-methyl-N1-(3-methylbutyl)-8-oxo-7-propyl-5H,6H,7H,8H-imidazo[1,5-a]pyrazine-1,6-dicarboxamide

G282-1948 Screening compound: N6-[(4-fluorophenyl)methyl]-6-methyl-N1-(3-methylbutyl)-8-oxo-7-propyl-5H,6H,7H,8H-imidazo[1,5-a]pyrazine-1,6-dicarboxamide
G282-1948 Screening compound: N6-[(4-fluorophenyl)methyl]-6-methyl-N1-(3-methylbutyl)-8-oxo-7-propyl-5H,6H,7H,8H-imidazo[1,5-a]pyrazine-1,6-dicarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G282-1948
N6-[(4-fluorophenyl)methyl]-6-methyl-N1-(3-methylbutyl)-8-oxo-7-propyl-5H,6H,7H,8H-imidazo[1,5-a]pyrazine-1,6-dicarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G282-1948

Molecular Formula

C24H32FN5O3 (C24 H32 FN5 O3)

Compound Name

N6-[(4-fluorophenyl)methyl]-6-methyl-N1-(3-methylbutyl)-8-oxo-7-propyl-5H,6H,7H,8H-imidazo[1,5-a]pyrazine-1,6-dicarboxamide

IUPAC name

N6-[(4-fluorophenyl)methyl]-6-methyl-N1-(3-methylbutyl)-8-oxo-7-propyl-5H6H7H8H-imidazo[15-a]pyrazine-16-dicarboxamide

SMILES

CCCN(C(C)(Cn1c2c(C(NCCC(C)C)=O)nc1)C(NCc(cc1)ccc1F)=O)C2=O

InChI

InChI=1S/C24H32FN5O3/c1-5-12-30-22(32)20-19(21(31)26-11-10-16(2)3)28-15-29(20)14-24(30,4)23(33)27-13-17-6-8-18(25)9-7-17/h6-9,15-16H,5,10-14H2,1-4H3,(H,26,31)(H,27,33)/t24-/m0/s1

InChI Key

CFGQPVZIGGZXGJ-DEOSSOPVSA-N

MDL Number (MFCD)

MFCD27212841

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

457.55

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

11.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.497

Distribution Coefficient, logD

2.497

Water Solubility, LogSw

-2.74

Polar Surface Area

76.461

Acid Dissociation Constant (pKa)

11.91

Base Dissociation Constant (pKb)

1.48

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

50.00

G282-1948 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Cyclic Ugi PPI Library (9586 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Protein-Protein Interaction Library (218420 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
  • Mimetics
  • Mimetics
  • Mimetics

References: we are preparing a list of scientific research reports with G282-1948 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G282-1948?
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What is the minimum amount of G282-1948 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G282-1948
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G282-1948
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G282-1948 available by request