G282-2946 Screening compound: N1-(4-acetylphenyl)-N6-cyclopentyl-7-ethyl-6-methyl-8-oxo-5H,6H,7H,8H-imidazo[1,5-a]pyrazine-1,6-dicarboxamide

G282-2946 Screening compound: N1-(4-acetylphenyl)-N6-cyclopentyl-7-ethyl-6-methyl-8-oxo-5H,6H,7H,8H-imidazo[1,5-a]pyrazine-1,6-dicarboxamide
G282-2946 Screening compound: N1-(4-acetylphenyl)-N6-cyclopentyl-7-ethyl-6-methyl-8-oxo-5H,6H,7H,8H-imidazo[1,5-a]pyrazine-1,6-dicarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G282-2946
N1-(4-acetylphenyl)-N6-cyclopentyl-7-ethyl-6-methyl-8-oxo-5H,6H,7H,8H-imidazo[1,5-a]pyrazine-1,6-dicarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G282-2946

Molecular Formula

C24H29N5O4 (C24 H29 N5 O4)

Compound Name

N1-(4-acetylphenyl)-N6-cyclopentyl-7-ethyl-6-methyl-8-oxo-5H,6H,7H,8H-imidazo[1,5-a]pyrazine-1,6-dicarboxamide

IUPAC name

N1-(4-acetylphenyl)-N6-cyclopentyl-7-ethyl-6-methyl-8-oxo-5H6H7H8H-imidazo[15-a]pyrazine-16-dicarboxamide

SMILES

CCN(C(C)(Cn1c2c(C(Nc(cc3)ccc3C(C)=O)=O)nc1)C(NC1CCCC1)=O)C2=O

InChI

InChI=1S/C24H29N5O4/c1-4-29-22(32)20-19(21(31)26-18-11-9-16(10-12-18)15(2)30)25-14-28(20)13-24(29,3)23(33)27-17-7-5-6-8-17/h9-12,14,17H,4-8,13H2,1-3H3,(H,26,31)(H,27,33)/t24-/m0/s1

InChI Key

BHIWKACAQVGDSZ-DEOSSOPVSA-N

MDL Number (MFCD)

MFCD27212910

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

451.53

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

1.806

Distribution Coefficient, logD

1.806

Water Solubility, LogSw

-2.44

Polar Surface Area

88.690

Acid Dissociation Constant (pKa)

10.40

Base Dissociation Constant (pKb)

1.60

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

45.80

G282-2946 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Cyclic Ugi PPI Library (9586 compounds)

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Protein-Protein Interaction Library (218420 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
  • Mimetics
  • Mimetics

References: we are preparing a list of scientific research reports with G282-2946 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G282-2946?
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What is the minimum amount of G282-2946 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G282-2946
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G282-2946
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G282-2946 available by request