G282-6831 Screening compound: N1-[(3-chlorophenyl)methyl]-7-cyclopropyl-N6-[(4-fluorophenyl)methyl]-6-methyl-8-oxo-5H,6H,7H,8H-imidazo[1,5-a]pyrazine-1,6-dicarboxamide

G282-6831 Screening compound: N1-[(3-chlorophenyl)methyl]-7-cyclopropyl-N6-[(4-fluorophenyl)methyl]-6-methyl-8-oxo-5H,6H,7H,8H-imidazo[1,5-a]pyrazine-1,6-dicarboxamide
G282-6831 Screening compound: N1-[(3-chlorophenyl)methyl]-7-cyclopropyl-N6-[(4-fluorophenyl)methyl]-6-methyl-8-oxo-5H,6H,7H,8H-imidazo[1,5-a]pyrazine-1,6-dicarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G282-6831
N1-[(3-chlorophenyl)methyl]-7-cyclopropyl-N6-[(4-fluorophenyl)methyl]-6-methyl-8-oxo-5H,6H,7H,8H-imidazo[1,5-a]pyrazine-1,6-dicarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G282-6831

Molecular Formula

C26H25ClFN5O3 (C26 H25 ClFN5 O3)

Compound Name

N1-[(3-chlorophenyl)methyl]-7-cyclopropyl-N6-[(4-fluorophenyl)methyl]-6-methyl-8-oxo-5H,6H,7H,8H-imidazo[1,5-a]pyrazine-1,6-dicarboxamide

IUPAC name

N1-[(3-chlorophenyl)methyl]-7-cyclopropyl-N6-[(4-fluorophenyl)methyl]-6-methyl-8-oxo-5H6H7H8H-imidazo[15-a]pyrazine-16-dicarboxamide

SMILES

CC(Cn1c2c(C(NCc3cccc(Cl)c3)=O)nc1)(C(NCc(cc1)ccc1F)=O)N(C1CC1)C2=O

InChI

InChI=1S/C26H25ClFN5O3/c1-26(25(36)30-12-16-5-7-19(28)8-6-16)14-32-15-31-21(22(32)24(35)33(26)20-9-10-20)23(34)29-13-17-3-2-4-18(27)11-17/h2-8,11,15,20H,9-10,12-14H2,1H3,(H,29,34)(H,30,36)/t26-/m0/s1

InChI Key

SMIPLHBJIQISLP-SANMLTNESA-N

MDL Number (MFCD)

MFCD27213090

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

509.97

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.801

Distribution Coefficient, logD

2.801

Water Solubility, LogSw

-3.47

Polar Surface Area

75.651

Acid Dissociation Constant (pKa)

11.91

Base Dissociation Constant (pKb)

-0.16

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

30.80

G282-6831 in Drug Discovery

Included in Screening Libraries

Cyclic Ugi PPI Library (9586 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Protein-Protein Interaction Library (218420 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
  • Mimetics
  • Mimetics
  • Mimetics

References: we are preparing a list of scientific research reports with G282-6831 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G282-6831?
Check Price and Availability of G282-6831, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G282-6831 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G282-6831
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G282-6831
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G282-6831 available by request