G282-6860 Screening compound: N1-[(2-chlorophenyl)methyl]-7-cyclopropyl-N6-[(4-fluorophenyl)methyl]-6-methyl-8-oxo-5H,6H,7H,8H-imidazo[1,5-a]pyrazine-1,6-dicarboxamide

G282-6860 Screening compound: N1-[(2-chlorophenyl)methyl]-7-cyclopropyl-N6-[(4-fluorophenyl)methyl]-6-methyl-8-oxo-5H,6H,7H,8H-imidazo[1,5-a]pyrazine-1,6-dicarboxamide
G282-6860 Screening compound: N1-[(2-chlorophenyl)methyl]-7-cyclopropyl-N6-[(4-fluorophenyl)methyl]-6-methyl-8-oxo-5H,6H,7H,8H-imidazo[1,5-a]pyrazine-1,6-dicarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G282-6860
N1-[(2-chlorophenyl)methyl]-7-cyclopropyl-N6-[(4-fluorophenyl)methyl]-6-methyl-8-oxo-5H,6H,7H,8H-imidazo[1,5-a]pyrazine-1,6-dicarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G282-6860

Molecular Formula

C26H25ClFN5O3 (C26 H25 ClFN5 O3)

Compound Name

N1-[(2-chlorophenyl)methyl]-7-cyclopropyl-N6-[(4-fluorophenyl)methyl]-6-methyl-8-oxo-5H,6H,7H,8H-imidazo[1,5-a]pyrazine-1,6-dicarboxamide

IUPAC name

N1-[(2-chlorophenyl)methyl]-7-cyclopropyl-N6-[(4-fluorophenyl)methyl]-6-methyl-8-oxo-5H6H7H8H-imidazo[15-a]pyrazine-16-dicarboxamide

SMILES

CC(Cn1c2c(C(NCc(cccc3)c3Cl)=O)nc1)(C(NCc(cc1)ccc1F)=O)N(C1CC1)C2=O

InChI

InChI=1S/C26H25ClFN5O3/c1-26(25(36)30-12-16-6-8-18(28)9-7-16)14-32-15-31-21(22(32)24(35)33(26)19-10-11-19)23(34)29-13-17-4-2-3-5-20(17)27/h2-9,15,19H,10-14H2,1H3,(H,29,34)(H,30,36)/t26-/m0/s1

InChI Key

SLMHERVQTGPBQX-SANMLTNESA-N

MDL Number (MFCD)

MFCD27213096

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

509.97

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.886

Distribution Coefficient, logD

2.886

Water Solubility, LogSw

-3.34

Polar Surface Area

75.651

Acid Dissociation Constant (pKa)

11.91

Base Dissociation Constant (pKb)

-0.16

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

30.80

G282-6860 in Drug Discovery

Included in Screening Libraries

Cyclic Ugi PPI Library (9586 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Protein-Protein Interaction Library (218420 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
  • Mimetics
  • Mimetics
  • Mimetics

References: we are preparing a list of scientific research reports with G282-6860 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G282-6860?
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What is the minimum amount of G282-6860 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G282-6860
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G282-6860
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G282-6860 available by request