G282-6885 Screening compound: methyl 2-(7-cyclopropyl-6-{[(4-fluorophenyl)methyl]carbamoyl}-6-methyl-8-oxo-5H,6H,7H,8H-imidazo[1,5-a]pyrazine-1-amido)benzoate

G282-6885 Screening compound: methyl 2-(7-cyclopropyl-6-{[(4-fluorophenyl)methyl]carbamoyl}-6-methyl-8-oxo-5H,6H,7H,8H-imidazo[1,5-a]pyrazine-1-amido)benzoate
G282-6885 Screening compound: methyl 2-(7-cyclopropyl-6-{[(4-fluorophenyl)methyl]carbamoyl}-6-methyl-8-oxo-5H,6H,7H,8H-imidazo[1,5-a]pyrazine-1-amido)benzoate alternative view

Chemical Structure Depiction of ChemDiv screening compound G282-6885
methyl 2-(7-cyclopropyl-6-{[(4-fluorophenyl)methyl]carbamoyl}-6-methyl-8-oxo-5H,6H,7H,8H-imidazo[1,5-a]pyrazine-1-amido)benzoate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G282-6885

Molecular Formula

C27H26FN5O5 (C27 H26 FN5 O5)

Compound Name

methyl 2-(7-cyclopropyl-6-{[(4-fluorophenyl)methyl]carbamoyl}-6-methyl-8-oxo-5H,6H,7H,8H-imidazo[1,5-a]pyrazine-1-amido)benzoate

IUPAC name

methyl 2-(7-cyclopropyl-6-{[(4-fluorophenyl)methyl]carbamoyl}-6-methyl-8-oxo-5H6H7H8H-imidazo[15-a]pyrazine-1-amido)benzoate

SMILES

CC(Cn1c2c(C(Nc(cccc3)c3C(OC)=O)=O)nc1)(C(NCc(cc1)ccc1F)=O)N(C1CC1)C2=O

InChI

InChI=1S/C27H26FN5O5/c1-27(26(37)29-13-16-7-9-17(28)10-8-16)14-32-15-30-21(22(32)24(35)33(27)18-11-12-18)23(34)31-20-6-4-3-5-19(20)25(36)38-2/h3-10,15,18H,11-14H2,1-2H3,(H,29,37)(H,31,34)/t27-/m0/s1

InChI Key

AVJVLNZAWRIKDR-MHZLTWQESA-N

MDL Number (MFCD)

MFCD27213109

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

519.53

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

2.435

Distribution Coefficient, logD

2.408

Water Solubility, LogSw

-3.04

Polar Surface Area

94.805

Acid Dissociation Constant (pKa)

8.59

Base Dissociation Constant (pKb)

0.46

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

29.60

G282-6885 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Cyclic Ugi PPI Library (9586 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Protein-Protein Interaction Library (218420 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
  • Mimetics
  • Mimetics
  • Mimetics

References: we are preparing a list of scientific research reports with G282-6885 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G282-6885?
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What is the minimum amount of G282-6885 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G282-6885
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G282-6885
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G282-6885 available by request