G282-6965 Screening compound: 7-cyclopropyl-N6-[(4-fluorophenyl)methyl]-6-methyl-N1-[(5-methylfuran-2-yl)methyl]-8-oxo-5H,6H,7H,8H-imidazo[1,5-a]pyrazine-1,6-dicarboxamide

G282-6965 Screening compound: 7-cyclopropyl-N6-[(4-fluorophenyl)methyl]-6-methyl-N1-[(5-methylfuran-2-yl)methyl]-8-oxo-5H,6H,7H,8H-imidazo[1,5-a]pyrazine-1,6-dicarboxamide
G282-6965 Screening compound: 7-cyclopropyl-N6-[(4-fluorophenyl)methyl]-6-methyl-N1-[(5-methylfuran-2-yl)methyl]-8-oxo-5H,6H,7H,8H-imidazo[1,5-a]pyrazine-1,6-dicarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G282-6965
7-cyclopropyl-N6-[(4-fluorophenyl)methyl]-6-methyl-N1-[(5-methylfuran-2-yl)methyl]-8-oxo-5H,6H,7H,8H-imidazo[1,5-a]pyrazine-1,6-dicarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G282-6965

Molecular Formula

C25H26FN5O4 (C25 H26 FN5 O4)

Compound Name

7-cyclopropyl-N6-[(4-fluorophenyl)methyl]-6-methyl-N1-[(5-methylfuran-2-yl)methyl]-8-oxo-5H,6H,7H,8H-imidazo[1,5-a]pyrazine-1,6-dicarboxamide

IUPAC name

7-cyclopropyl-N6-[(4-fluorophenyl)methyl]-6-methyl-N1-[(5-methylfuran-2-yl)methyl]-8-oxo-5H6H7H8H-imidazo[15-a]pyrazine-16-dicarboxamide

SMILES

CC(Cn1c2c(C(NCc3ccc(C)o3)=O)nc1)(C(NCc(cc1)ccc1F)=O)N(C1CC1)C2=O

InChI

InChI=1S/C25H26FN5O4/c1-15-3-10-19(35-15)12-27-22(32)20-21-23(33)31(18-8-9-18)25(2,13-30(21)14-29-20)24(34)28-11-16-4-6-17(26)7-5-16/h3-7,10,14,18H,8-9,11-13H2,1-2H3,(H,27,32)(H,28,34)/t25-/m0/s1

InChI Key

VBSRYXDQMZTOOV-VWLOTQADSA-N

MDL Number (MFCD)

MFCD27213137

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

479.51

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.161

Distribution Coefficient, logD

2.161

Water Solubility, LogSw

-2.64

Polar Surface Area

82.914

Acid Dissociation Constant (pKa)

11.91

Base Dissociation Constant (pKb)

0.27

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

36.00

G282-6965 in Drug Discovery

Included in Screening Libraries

Cyclic Ugi PPI Library (9586 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Protein-Protein Interaction Library (218420 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
  • Mimetics
  • Mimetics
  • Mimetics

References: we are preparing a list of scientific research reports with G282-6965 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G282-6965?
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What is the minimum amount of G282-6965 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G282-6965
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G282-6965
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G282-6965 available by request