G282-7166 Screening compound: 7-cyclopropyl-N6-[(4-methoxyphenyl)methyl]-6-methyl-8-oxo-N1-(5,6,7,8-tetrahydronaphthalen-1-yl)-5H,6H,7H,8H-imidazo[1,5-a]pyrazine-1,6-dicarboxamide

Chemical Structure Depiction of ChemDiv screening compound G282-7166
7-cyclopropyl-N6-[(4-methoxyphenyl)methyl]-6-methyl-8-oxo-N1-(5,6,7,8-tetrahydronaphthalen-1-yl)-5H,6H,7H,8H-imidazo[1,5-a]pyrazine-1,6-dicarboxamide

Available from 1 mg

Formats:

Glass Vials (4ml Glass Vials VWR #97047-678)
96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

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Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G282-7166

Molecular Formula

C₃₀H₃₃N₅O₄ (C30 H33 N5 O4)

Compound Name

7-cyclopropyl-N6-[(4-methoxyphenyl)methyl]-6-methyl-8-oxo-N1-(5,6,7,8-tetrahydronaphthalen-1-yl)-5H,6H,7H,8H-imidazo[1,5-a]pyrazine-1,6-dicarboxamide

IUPAC name

7-cyclopropyl-N6-[(4-methoxyphenyl)methyl]-6-methyl-8-oxo-N1-(5678-tetrahydronaphthalen-1-yl)-5H6H7H8H-imidazo[15-a]pyrazine-16-dicarboxamide

SMILES

CC(Cn1c2c(C(Nc3c(CCCC4)c4ccc3)=O)nc1)(C(NCc(cc1)ccc1OC)=O)N(C1CC1)C2=O

InChI

InChI=1S/C30H33N5O4/c1-30(29(38)31-16-19-10-14-22(39-2)15-11-19)17-34-18-32-25(26(34)28(37)35(30)21-12-13-21)27(36)33-24-9-5-7-20-6-3-4-8-23(20)24/h5,7,9-11,14-15,18,21H,3-4,6,8,12-13,16-17H2,1-2H3,(H,31,38)(H,33,36)/t30-/m0/s1

InChI Key

GPIARUHCFKLDPN-PMERELPUSA-N

MDL Number (MFCD)

MFCD27213190

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

527.62

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

Partition Coefficient, logP

3.700

Distribution Coefficient, logD

3.700

Water Solubility, LogSw

-3.94

Polar Surface Area

81.095

Acid Dissociation Constant (pK_a)

12.91

Base Dissociation Constant (pK_b)

1.66

Number of Chiral Centers

1.00

Percent sp³ carbon bonding

40.00

G282-7166 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Cyclic Ugi PPI Library (9586 compounds)

GPCR Targeted Library (31838 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Protein-Protein Interaction Library (218420 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:

Cancer
Musculoskeletal
Respiratory tract
Nervous system
Congenital
Skin
Metabolic
Endocrine

Mechanism of action:

PPI modulators
Receptor's ligands
PPI modulators
PPI modulators
PPI modulators
PPI modulators

Structure:

Cyclic compounds
Mimetics
Mimetics
Mimetics

Targets:

GPCR

References: we are preparing a list of scientific research reports with G282-7166 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G282-7166?
Check Price and Availability of G282-7166, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.

What is the minimum amount of G282-7166 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.

Delivery options for G282-7166
ChemDiv sends parcels with Express services (UPS, WC).

1–2 days for small orders
2–4 weeks for large selections

Delivery formats for G282-7166

0.5–50 mg of dry powder sample in single glass vials, custom vials
DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G282-7166 available by request