G282-8073 Screening compound: 7-cyclopropyl-6-methyl-8-oxo-N6-[3-(propan-2-yloxy)propyl]-N1-[2-(trifluoromethyl)phenyl]-5H,6H,7H,8H-imidazo[1,5-a]pyrazine-1,6-dicarboxamide

G282-8073 Screening compound: 7-cyclopropyl-6-methyl-8-oxo-N6-[3-(propan-2-yloxy)propyl]-N1-[2-(trifluoromethyl)phenyl]-5H,6H,7H,8H-imidazo[1,5-a]pyrazine-1,6-dicarboxamide
G282-8073 Screening compound: 7-cyclopropyl-6-methyl-8-oxo-N6-[3-(propan-2-yloxy)propyl]-N1-[2-(trifluoromethyl)phenyl]-5H,6H,7H,8H-imidazo[1,5-a]pyrazine-1,6-dicarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G282-8073
7-cyclopropyl-6-methyl-8-oxo-N6-[3-(propan-2-yloxy)propyl]-N1-[2-(trifluoromethyl)phenyl]-5H,6H,7H,8H-imidazo[1,5-a]pyrazine-1,6-dicarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G282-8073

Molecular Formula

C25H30F3N5O4 (C25 H30 F3 N5 O4)

Compound Name

7-cyclopropyl-6-methyl-8-oxo-N6-[3-(propan-2-yloxy)propyl]-N1-[2-(trifluoromethyl)phenyl]-5H,6H,7H,8H-imidazo[1,5-a]pyrazine-1,6-dicarboxamide

IUPAC name

7-cyclopropyl-6-methyl-8-oxo-N6-[3-(propan-2-yloxy)propyl]-N1-[2-(trifluoromethyl)phenyl]-5H6H7H8H-imidazo[15-a]pyrazine-16-dicarboxamide

SMILES

CC(C)OCCCNC(C(C)(Cn1c2c(C(Nc3c(C(F)(F)F)cccc3)=O)nc1)N(C1CC1)C2=O)=O

InChI

InChI=1S/C25H30F3N5O4/c1-15(2)37-12-6-11-29-23(36)24(3)13-32-14-30-19(20(32)22(35)33(24)16-9-10-16)21(34)31-18-8-5-4-7-17(18)25(26,27)28/h4-5,7-8,14-16H,6,9-13H2,1-3H3,(H,29,36)(H,31,34)/t24-/m0/s1

InChI Key

OKNWMQHZUOLIQE-DEOSSOPVSA-N

MDL Number (MFCD)

MFCD27213270

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

521.54

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

12.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.364

Distribution Coefficient, logD

2.364

Water Solubility, LogSw

-3.11

Polar Surface Area

80.945

Acid Dissociation Constant (pKa)

12.26

Base Dissociation Constant (pKb)

1.66

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

52.00

G282-8073 in Drug Discovery

Included in Screening Libraries

Cyclic Ugi PPI Library (9586 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Protein-Protein Interaction Library (218420 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
  • Mimetics
  • Mimetics
  • Mimetics

References: we are preparing a list of scientific research reports with G282-8073 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G282-8073?
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What is the minimum amount of G282-8073 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G282-8073
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G282-8073
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G282-8073 available by request