G283-0078 Screening compound: N~1~-(3,4-dimethylphenyl)-2-{[5-(4-ethylphenyl)-4-methyl-1,1-dioxo-1H-1lambda~6~-isothiazol-3-yl]amino}acetamide

G283-0078 Screening compound: N~1~-(3,4-dimethylphenyl)-2-{[5-(4-ethylphenyl)-4-methyl-1,1-dioxo-1H-1lambda~6~-isothiazol-3-yl]amino}acetamide
G283-0078 Screening compound: N~1~-(3,4-dimethylphenyl)-2-{[5-(4-ethylphenyl)-4-methyl-1,1-dioxo-1H-1lambda~6~-isothiazol-3-yl]amino}acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G283-0078
N~1~-(3,4-dimethylphenyl)-2-{[5-(4-ethylphenyl)-4-methyl-1,1-dioxo-1H-1lambda~6~-isothiazol-3-yl]amino}acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G283-0078

Molecular Formula

C22H25N3O3S (C22 H25 N3 O3 S)

Compound Name

N~1~-(3,4-dimethylphenyl)-2-{[5-(4-ethylphenyl)-4-methyl-1,1-dioxo-1H-1lambda~6~-isothiazol-3-yl]amino}acetamide

IUPAC name

N-(34-dimethylphenyl)-2-{[5-(4-ethylphenyl)-4-methyl-11-dioxo-1lambda62-thiazol-3-yl]amino}acetamide

SMILES

CCc(cc1)ccc1C1=C(C)C(NCC(Nc2cc(C)c(C)cc2)=O)=NS1(=O)=O

InChI

InChI=1S/C22H25N3O3S/c1-5-17-7-9-18(10-8-17)21-16(4)22(25-29(21,27)28)23-13-20(26)24-19-11-6-14(2)15(3)12-19/h6-12H,5,13H2,1-4H3,(H,23,25)(H,24,26)

InChI Key

NYTVMNMDPARXSP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14994465

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

411.52

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.758

Distribution Coefficient, logD

4.758

Water Solubility, LogSw

-4.48

Polar Surface Area

75.316

Acid Dissociation Constant (pKa)

11.41

Base Dissociation Constant (pKb)

-0.15

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.30

G283-0078 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

Arginase Targeted Library (2009 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Cancer
  • Musculoskeletal
  • Male
  • Cardiovascular
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Mechanism of action:
  • Epigenetic
  • Epigenetic
Targets:
  • Others
  • Others

References: we are preparing a list of scientific research reports with G283-0078 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G283-0078?
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What is the minimum amount of G283-0078 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G283-0078
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G283-0078
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G283-0078 available by request