G283-1134 Screening compound: 2-{[5-(4-chlorophenyl)-4-methyl-1,1-dioxo-1H-1lambda~6~-isothiazol-3-yl]amino}-N~1~-(2-thienylmethyl)acetamide

G283-1134 Screening compound: 2-{[5-(4-chlorophenyl)-4-methyl-1,1-dioxo-1H-1lambda~6~-isothiazol-3-yl]amino}-N~1~-(2-thienylmethyl)acetamide
G283-1134 Screening compound: 2-{[5-(4-chlorophenyl)-4-methyl-1,1-dioxo-1H-1lambda~6~-isothiazol-3-yl]amino}-N~1~-(2-thienylmethyl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G283-1134
2-{[5-(4-chlorophenyl)-4-methyl-1,1-dioxo-1H-1lambda~6~-isothiazol-3-yl]amino}-N~1~-(2-thienylmethyl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G283-1134

Molecular Formula

C17H16ClN3O3S2 (C17 H16 ClN3 O3 S2)

Compound Name

2-{[5-(4-chlorophenyl)-4-methyl-1,1-dioxo-1H-1lambda~6~-isothiazol-3-yl]amino}-N~1~-(2-thienylmethyl)acetamide

IUPAC name

2-{[5-(4-chlorophenyl)-4-methyl-11-dioxo-1lambda62-thiazol-3-yl]amino}-N-[(thiophen-2-yl)methyl]acetamide

SMILES

CC(C(NCC(NCc1cccs1)=O)=N1)=C(c(cc2)ccc2Cl)S1(=O)=O

InChI

InChI=1S/C17H16ClN3O3S2/c1-11-16(12-4-6-13(18)7-5-12)26(23,24)21-17(11)20-10-15(22)19-9-14-3-2-8-25-14/h2-8H,9-10H2,1H3,(H,19,22)(H,20,21)

InChI Key

FLMWCAFKSSHYEN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14994566

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

409.92

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.232

Distribution Coefficient, logD

3.232

Water Solubility, LogSw

-3.80

Polar Surface Area

77.656

Acid Dissociation Constant (pKa)

12.00

Base Dissociation Constant (pKb)

-3.20

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

17.60

G283-1134 in Drug Discovery

Included in Screening Libraries

Protein Arginine Methyltransferases Library (27925 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic
Agro:
  • Agro

References: we are preparing a list of scientific research reports with G283-1134 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G283-1134?
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What is the minimum amount of G283-1134 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G283-1134
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G283-1134
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G283-1134 available by request