G283-1288 Screening compound: 2-{[5-(4-chlorophenyl)-4-methyl-1,1-dioxo-1H-1lambda~6~-isothiazol-3-yl]amino}-N~1~-(2,5-dimethoxybenzyl)acetamide

G283-1288 Screening compound: 2-{[5-(4-chlorophenyl)-4-methyl-1,1-dioxo-1H-1lambda~6~-isothiazol-3-yl]amino}-N~1~-(2,5-dimethoxybenzyl)acetamide
G283-1288 Screening compound: 2-{[5-(4-chlorophenyl)-4-methyl-1,1-dioxo-1H-1lambda~6~-isothiazol-3-yl]amino}-N~1~-(2,5-dimethoxybenzyl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G283-1288
2-{[5-(4-chlorophenyl)-4-methyl-1,1-dioxo-1H-1lambda~6~-isothiazol-3-yl]amino}-N~1~-(2,5-dimethoxybenzyl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G283-1288

Molecular Formula

C21H22ClN3O5S (C21 H22 ClN3 O5 S)

Compound Name

2-{[5-(4-chlorophenyl)-4-methyl-1,1-dioxo-1H-1lambda~6~-isothiazol-3-yl]amino}-N~1~-(2,5-dimethoxybenzyl)acetamide

IUPAC name

2-{[5-(4-chlorophenyl)-4-methyl-11-dioxo-1lambda62-thiazol-3-yl]amino}-N-[(25-dimethoxyphenyl)methyl]acetamide

SMILES

CC(C(NCC(NCc(cc(cc1)OC)c1OC)=O)=N1)=C(c(cc2)ccc2Cl)S1(=O)=O

InChI

InChI=1S/C21H22ClN3O5S/c1-13-20(14-4-6-16(22)7-5-14)31(27,28)25-21(13)24-12-19(26)23-11-15-10-17(29-2)8-9-18(15)30-3/h4-10H,11-12H2,1-3H3,(H,23,26)(H,24,25)

InChI Key

IYRUCZMMAPXJBP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14994575

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

463.94

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.457

Distribution Coefficient, logD

3.457

Water Solubility, LogSw

-4.08

Polar Surface Area

91.812

Acid Dissociation Constant (pKa)

12.00

Base Dissociation Constant (pKb)

-1.91

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

23.80

G283-1288 in Drug Discovery

Included in Screening Libraries

Protein Arginine Methyltransferases Library (27925 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with G283-1288 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G283-1288?
Check Price and Availability of G283-1288, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G283-1288 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G283-1288
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G283-1288
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G283-1288 available by request