G284-1258 Screening compound: N-(4-bromo-2-fluorophenyl)-4-[4,6-dimethyl-3-(1H-pyrrol-1-yl)-1H-pyrazolo[3,4-b]pyridin-1-yl]butanamide

G284-1258 Screening compound: N-(4-bromo-2-fluorophenyl)-4-[4,6-dimethyl-3-(1H-pyrrol-1-yl)-1H-pyrazolo[3,4-b]pyridin-1-yl]butanamide
G284-1258 Screening compound: N-(4-bromo-2-fluorophenyl)-4-[4,6-dimethyl-3-(1H-pyrrol-1-yl)-1H-pyrazolo[3,4-b]pyridin-1-yl]butanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G284-1258
N-(4-bromo-2-fluorophenyl)-4-[4,6-dimethyl-3-(1H-pyrrol-1-yl)-1H-pyrazolo[3,4-b]pyridin-1-yl]butanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G284-1258

Molecular Formula

C22H21BrFN5O (C22 H21 BrFN5 O)

Compound Name

N-(4-bromo-2-fluorophenyl)-4-[4,6-dimethyl-3-(1H-pyrrol-1-yl)-1H-pyrazolo[3,4-b]pyridin-1-yl]butanamide

IUPAC name

N-(4-bromo-2-fluorophenyl)-4-[46-dimethyl-3-(1H-pyrrol-1-yl)-1H-pyrazolo[34-b]pyridin-1-yl]butanamide

SMILES

Cc1c(c(-n2cccc2)nn2CCCC(Nc(ccc(Br)c3)c3F)=O)c2nc(C)c1

InChI

InChI=1S/C22H21BrFN5O/c1-14-12-15(2)25-21-20(14)22(28-9-3-4-10-28)27-29(21)11-5-6-19(30)26-18-8-7-16(23)13-17(18)24/h3-4,7-10,12-13H,5-6,11H2,1-2H3,(H,26,30)

InChI Key

DDLTZHYWOKFBCQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14994799

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

470.34

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.176

Distribution Coefficient, logD

4.128

Water Solubility, LogSw

-4.35

Polar Surface Area

49.076

Acid Dissociation Constant (pKa)

8.37

Base Dissociation Constant (pKb)

5.30

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

22.70

G284-1258 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with G284-1258 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G284-1258?
Check Price and Availability of G284-1258, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G284-1258 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G284-1258
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G284-1258
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G284-1258 available by request