G284-2127 Screening compound: 4-{[4,6-dimethyl-3-(1H-pyrrol-1-yl)-1H-pyrazolo[3,4-b]pyridin-1-yl]methyl}-N-(3-methylbutyl)benzamide

G284-2127 Screening compound: 4-{[4,6-dimethyl-3-(1H-pyrrol-1-yl)-1H-pyrazolo[3,4-b]pyridin-1-yl]methyl}-N-(3-methylbutyl)benzamide
G284-2127 Screening compound: 4-{[4,6-dimethyl-3-(1H-pyrrol-1-yl)-1H-pyrazolo[3,4-b]pyridin-1-yl]methyl}-N-(3-methylbutyl)benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G284-2127
4-{[4,6-dimethyl-3-(1H-pyrrol-1-yl)-1H-pyrazolo[3,4-b]pyridin-1-yl]methyl}-N-(3-methylbutyl)benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G284-2127

Molecular Formula

C25H29N5O (C25 H29 N5 O)

Compound Name

4-{[4,6-dimethyl-3-(1H-pyrrol-1-yl)-1H-pyrazolo[3,4-b]pyridin-1-yl]methyl}-N-(3-methylbutyl)benzamide

IUPAC name

4-{[46-dimethyl-3-(1H-pyrrol-1-yl)-1H-pyrazolo[34-b]pyridin-1-yl]methyl}-N-(3-methylbutyl)benzamide

SMILES

CC(C)CCNC(c1ccc(Cn(c2nc(C)cc(C)c22)nc2-n2cccc2)cc1)=O

InChI

InChI=1S/C25H29N5O/c1-17(2)11-12-26-25(31)21-9-7-20(8-10-21)16-30-23-22(18(3)15-19(4)27-23)24(28-30)29-13-5-6-14-29/h5-10,13-15,17H,11-12,16H2,1-4H3,(H,26,31)

InChI Key

QFJIFURWHCLZEN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14994870

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

415.54

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.666

Distribution Coefficient, logD

4.641

Water Solubility, LogSw

-4.48

Polar Surface Area

51.173

Acid Dissociation Constant (pKa)

12.79

Base Dissociation Constant (pKb)

6.17

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

32.00

G284-2127 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with G284-2127 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G284-2127?
Check Price and Availability of G284-2127, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G284-2127 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G284-2127
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G284-2127
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G284-2127 available by request