G289-0068 Screening compound: 1-benzyl-4-{1-methyl-1H,4H,5H-thieno[2,3-g]indazole-3-carbonyl}piperazine

G289-0068 Screening compound: 1-benzyl-4-{1-methyl-1H,4H,5H-thieno[2,3-g]indazole-3-carbonyl}piperazine
G289-0068 Screening compound: 1-benzyl-4-{1-methyl-1H,4H,5H-thieno[2,3-g]indazole-3-carbonyl}piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound G289-0068
1-benzyl-4-{1-methyl-1H,4H,5H-thieno[2,3-g]indazole-3-carbonyl}piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G289-0068

Molecular Formula

C22H24N4OS (C22 H24 N4 OS)

Compound Name

1-benzyl-4-{1-methyl-1H,4H,5H-thieno[2,3-g]indazole-3-carbonyl}piperazine

IUPAC name

1-benzyl-4-{1-methyl-1H4H5H-thieno[23-g]indazole-3-carbonyl}piperazine

SMILES

Cn1nc(C(N2CCN(Cc3ccccc3)CC2)=O)c(CC2)c1-c1c2scc1

InChI

InChI=1S/C22H24N4OS/c1-24-21-17-9-14-28-19(17)8-7-18(21)20(23-24)22(27)26-12-10-25(11-13-26)15-16-5-3-2-4-6-16/h2-6,9,14H,7-8,10-13,15H2,1H3

InChI Key

REHHRMFLGQGAMR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14994984

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

392.52

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

2.836

Distribution Coefficient, logD

2.820

Water Solubility, LogSw

-3.34

Polar Surface Area

35.768

Acid Dissociation Constant (pKa)

20.16

Base Dissociation Constant (pKb)

5.96

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

36.40

G289-0068 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • Receptor's ligands
Therapeutical areas:
  • Immune system

References: we are preparing a list of scientific research reports with G289-0068 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G289-0068?
Check Price and Availability of G289-0068, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G289-0068 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G289-0068
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G289-0068
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G289-0068 available by request