G290-0271 Screening compound: 6-{2-[4-(2-fluorophenyl)piperazino]-2-oxoethyl}pyrido[2,3-b][1,5]benzothiazepin-5(6H)-one

G290-0271 Screening compound: 6-{2-[4-(2-fluorophenyl)piperazino]-2-oxoethyl}pyrido[2,3-b][1,5]benzothiazepin-5(6H)-one
G290-0271 Screening compound: 6-{2-[4-(2-fluorophenyl)piperazino]-2-oxoethyl}pyrido[2,3-b][1,5]benzothiazepin-5(6H)-one alternative view

Chemical Structure Depiction of ChemDiv screening compound G290-0271
6-{2-[4-(2-fluorophenyl)piperazino]-2-oxoethyl}pyrido[2,3-b][1,5]benzothiazepin-5(6H)-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G290-0271

Molecular Formula

C24H21FN4O2S (C24 H21 FN4 O2 S)

Compound Name

6-{2-[4-(2-fluorophenyl)piperazino]-2-oxoethyl}pyrido[2,3-b][1,5]benzothiazepin-5(6H)-one

IUPAC name

10-{2-[4-(2-fluorophenyl)piperazin-1-yl]-2-oxoethyl}-2-thia-410-diazatricyclo[9.4.0.0^{38}]pentadeca-1(11)3(8)461214-hexaen-9-one

SMILES

O=C(CN(c(cccc1)c1Sc1ncccc11)C1=O)N(CC1)CCN1c(cccc1)c1F

InChI

InChI=1S/C24H21FN4O2S/c25-18-7-1-2-8-19(18)27-12-14-28(15-13-27)22(30)16-29-20-9-3-4-10-21(20)32-23-17(24(29)31)6-5-11-26-23/h1-11H,12-16H2

InChI Key

PHTRBFOAARHNCN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14995197

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

448.52

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.428

Distribution Coefficient, logD

3.428

Water Solubility, LogSw

-3.88

Polar Surface Area

45.805

Acid Dissociation Constant (pKa)

21.28

Base Dissociation Constant (pKb)

4.43

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.80

G290-0271 in Drug Discovery

Included in Screening Libraries

Antiviral HBV Library (10007 compounds)

Antiviral Library (67538 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein-Protein Interaction Library (218420 compounds)

Recognition Elements PPI Library (24135 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Antiviral
  • Infections
  • Immune system
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with G290-0271 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G290-0271?
Check Price and Availability of G290-0271, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G290-0271 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G290-0271
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G290-0271
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G290-0271 available by request