G290-0292 Screening compound: N~1~-(2-chloro-4-fluorophenyl)-2-[5-oxopyrido[2,3-b][1,5]benzothiazepin-6(5H)-yl]acetamide

G290-0292 Screening compound: N~1~-(2-chloro-4-fluorophenyl)-2-[5-oxopyrido[2,3-b][1,5]benzothiazepin-6(5H)-yl]acetamide
G290-0292 Screening compound: N~1~-(2-chloro-4-fluorophenyl)-2-[5-oxopyrido[2,3-b][1,5]benzothiazepin-6(5H)-yl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G290-0292
N~1~-(2-chloro-4-fluorophenyl)-2-[5-oxopyrido[2,3-b][1,5]benzothiazepin-6(5H)-yl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G290-0292

Molecular Formula

C20H13ClFN3O2S (C20 H13 ClFN3 O2 S)

Compound Name

N~1~-(2-chloro-4-fluorophenyl)-2-[5-oxopyrido[2,3-b][1,5]benzothiazepin-6(5H)-yl]acetamide

IUPAC name

N-(2-chloro-4-fluorophenyl)-2-{9-oxo-2-thia-410-diazatricyclo[9.4.0.0^{38}]pentadeca-1(11)3(8)461214-hexaen-10-yl}acetamide

SMILES

O=C(CN(c(cccc1)c1Sc1c2cccn1)C2=O)Nc(ccc(F)c1)c1Cl

InChI

InChI=1S/C20H13ClFN3O2S/c21-14-10-12(22)7-8-15(14)24-18(26)11-25-16-5-1-2-6-17(16)28-19-13(20(25)27)4-3-9-23-19/h1-10H,11H2,(H,24,26)

InChI Key

AKMWTFUQQWHVKI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14995205

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

413.86

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.119

Distribution Coefficient, logD

4.109

Water Solubility, LogSw

-4.36

Polar Surface Area

48.905

Acid Dissociation Constant (pKa)

9.06

Base Dissociation Constant (pKb)

-0.27

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

5.00

G290-0292 in Drug Discovery

Included in Screening Libraries

Antiviral HBV Library (10007 compounds)

Antiviral Library (67538 compounds)

Immunological Library (6760 compounds)

Protein-Protein Interaction Library (218420 compounds)

Indoleamine 2,3-dioxygenase 1 Focused Library (5816 compounds)

Recognition Elements PPI Library (24135 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Antiviral
  • Infections
  • Immune system
  • Immune system
  • Cancer
  • Digestive system
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Immune system
Mechanism of action:
  • PPI modulators
  • PPI modulators
Targets:
  • Others
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with G290-0292 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G290-0292?
Check Price and Availability of G290-0292, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G290-0292 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G290-0292
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G290-0292
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G290-0292 available by request