G291-1433 Screening compound: 4-[4-(2,4-dimethylphenyl)piperazino]-6-(1-pyrrolidinyl)-5-pyrimidinecarbonitrile

G291-1433 Screening compound: 4-[4-(2,4-dimethylphenyl)piperazino]-6-(1-pyrrolidinyl)-5-pyrimidinecarbonitrile
G291-1433 Screening compound: 4-[4-(2,4-dimethylphenyl)piperazino]-6-(1-pyrrolidinyl)-5-pyrimidinecarbonitrile alternative view

Chemical Structure Depiction of ChemDiv screening compound G291-1433
4-[4-(2,4-dimethylphenyl)piperazino]-6-(1-pyrrolidinyl)-5-pyrimidinecarbonitrile

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G291-1433

Molecular Formula

C21H26N6 (C21 H26 N6)

Compound Name

4-[4-(2,4-dimethylphenyl)piperazino]-6-(1-pyrrolidinyl)-5-pyrimidinecarbonitrile

IUPAC name

4-[4-(24-dimethylphenyl)piperazin-1-yl]-6-(pyrrolidin-1-yl)pyrimidine-5-carbonitrile

SMILES

Cc(cc1)cc(C)c1N(CC1)CCN1c(ncnc1N2CCCC2)c1C#N

InChI

InChI=1S/C21H26N6/c1-16-5-6-19(17(2)13-16)25-9-11-27(12-10-25)21-18(14-22)20(23-15-24-21)26-7-3-4-8-26/h5-6,13,15H,3-4,7-12H2,1-2H3

InChI Key

FTVQPKWBIRNGPU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14995495

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

362.48

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.956

Distribution Coefficient, logD

4.956

Water Solubility, LogSw

-4.81

Polar Surface Area

47.201

Acid Dissociation Constant (pKa)

21.94

Base Dissociation Constant (pKb)

2.97

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

47.62

G291-1433 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with G291-1433 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G291-1433?
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What is the minimum amount of G291-1433 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G291-1433
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G291-1433
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G291-1433 available by request