G295-0694 Screening compound: N-(3-chlorobenzyl)-4-[(3,5-dimethyl-1H-pyrazol-1-yl)methyl]-5-methyl-3-isoxazolecarboxamide

G295-0694 Screening compound: N-(3-chlorobenzyl)-4-[(3,5-dimethyl-1H-pyrazol-1-yl)methyl]-5-methyl-3-isoxazolecarboxamide
G295-0694 Screening compound: N-(3-chlorobenzyl)-4-[(3,5-dimethyl-1H-pyrazol-1-yl)methyl]-5-methyl-3-isoxazolecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G295-0694
N-(3-chlorobenzyl)-4-[(3,5-dimethyl-1H-pyrazol-1-yl)methyl]-5-methyl-3-isoxazolecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G295-0694

Molecular Formula

C18H19ClN4O2 (C18 H19 ClN4 O2)

Compound Name

N-(3-chlorobenzyl)-4-[(3,5-dimethyl-1H-pyrazol-1-yl)methyl]-5-methyl-3-isoxazolecarboxamide

IUPAC name

N-[(3-chlorophenyl)methyl]-4-[(35-dimethyl-1H-pyrazol-1-yl)methyl]-5-methyl-12-oxazole-3-carboxamide

SMILES

Cc1cc(C)nn1Cc1c(C)onc1C(NCc1cccc(Cl)c1)=O

InChI

InChI=1S/C18H19ClN4O2/c1-11-7-12(2)23(21-11)10-16-13(3)25-22-17(16)18(24)20-9-14-5-4-6-15(19)8-14/h4-8H,9-10H2,1-3H3,(H,20,24)

InChI Key

NQFHCDDUIXKNSS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14995659

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

358.83

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.440

Distribution Coefficient, logD

2.439

Water Solubility, LogSw

-3.41

Polar Surface Area

60.619

Acid Dissociation Constant (pKa)

12.18

Base Dissociation Constant (pKb)

4.26

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.78

G295-0694 in Drug Discovery

Included in Screening Libraries

Glucocorticoid receptors Library (4806 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Endocrine
Targets:
  • Nuclear receptors
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G295-0694 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G295-0694?
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What is the minimum amount of G295-0694 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G295-0694
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G295-0694
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G295-0694 available by request